HTR1F 抗体
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北京 101111
Quick Overview for HTR1F 抗体 (ABIN121982)
抗原
See all HTR1F 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody reacts to Serotonin Receptor 1F (Family: GPCR, Subfamily: Serotonin).
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纯化方法
- Peptide immunogen affinity column
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免疫原
- Synthetic peptide - KLH conjugated
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应用备注
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Immunohistochemsiry on paraffin embedded sections: 5-8 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International. -
限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.7, containing 0.01 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-80 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- HTR1F (5-Hydroxytryptamine (serotonin) Receptor 1F (HTR1F))
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别名
- Serotonin Receptor 1F (HTR1F)
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背景
- 5-HT1F, a Serotonin Receptor, is negatively coupled to adenylate cyclase. Selective 5-HT1F agonists may prove therapeutic in the treatment of migraine headache, lacking the side effects associated with the agonists of the 5-HT1B and 5-HT1D receptors. Expression of the 5-HT1F receptor has been reported in various brain structures, including cortex, hippocampus, trigeminal ganglia, and cerebral blood vessels. Expression in peripheral tissues is limited to uterus, mesentery, and artery. No expression has been detected in heart, kidney, liver, pancreas, or spleen.Synonyms: 5-HT-1F, 5-hydroxytryptamine receptor 1F, HTR1EL
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基因ID
- 3355
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UniProt
- P30939
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途径
- JAK/STAT Signaling
抗原
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