我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

CXCR4 抗体 (Cytoplasmic Domain)

Name: CXCR4 抗体 (Cytoplasmic Domain)
SKU: ABIN121952
Availability: OutOfStock

The 兔多克隆 anti-CXCR4 antibody is suitable to detect CXCR4 in samples from 人, 小鼠和大鼠. It has been validated for IHC (p).

Staining of human tonsil using anti-CXCR4 antibody ABIN121952 (CXCR4 抗体 (Cytoplasmic Domain))

1 image

产品编号 ABIN121952

发货至: 中国

Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CXCR4 抗体 (Cytoplasmic Domain) (ABIN121952)

抗原

See all CXCR4 抗体

CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This CXCR4 antibody is un-conjugated

应用范围

Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product CXCR4 Primary Antibody

抗原表位
16

15

15

12

7

6

5

5

4

4

4

4

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cytoplasmic Domain

特异性

This antibody Detects human CXC Chemokine Receptor 4 (CXCR4, Family: GPCR, Subfamily: Chemokine).

纯化方法

Peptide Immunogen Affinity Chromatography.

免疫原

Synthetic peptide - KLH conjugated.

亚型

IgG
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 201-294) antibody
CXCR4 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-46) antibody
CXCR4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G9 unconjugated

anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 262-352) antibody
CXCR4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (N-Term) antibody
CXCR4 适用: 人, 小鼠, 兔, Pig, 马 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 14-40) antibody
CXCR4 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-356) antibody
CXCR4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (C-Term) antibody
CXCR4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-46) antibody
CXCR4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F8 unconjugated

anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) antibody (PE)
CXCR4 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal 12G5 PE

anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 2-15), (Extracellular) antibody
CXCR4 适用: 人 WB, IHC, FACS, IF, LCI, IC 宿主: 兔 Polyclonal unconjugated

应用备注

Immunohistochemistry on paraffin embedded sections: 9-14 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

限制

仅限研究用
浓度

1.0 mg/mL

缓冲液

PBS, pH 7.7 containing 0.09 % Sodium Azide as preservative.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

有效期

12 months
抗原

CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

别名

CD184 / CXCR4

背景

CXCR4, a Chemokine Receptor involved in organ vascularization, neuronal cell migration, and patterning of the central nervous system during development. It binds stromal cell-derived factor 1 (SDF1, also called PBFS) and mediates migration of resting leukocytes and is unique in homing hematopoietic progenitors to bone marrow. These properties suggest that CXCR4 is involved in tumor cell migration and local tumor invasion. It is also an HIV-1 fusion co-factor that allows HIV-1 invasion in diverse human cell types. Although this receptor was initially called Neuropeptide Y3 Receptor, it does not respond to neuropeptide Y. CXCR4 has two isoforms that are produced by alternative splicing. CXCR4 has been reported to be expressed in cells of the immune and central nervous systems. It is highly expressed in brain and heart, and in white blood cells, vascular endothelial cells, and umbilical cord endothelial cells. In brain tumors, CXCR4 is expressed in regions of angiogenesis and degenerative, necrotic, and microcystic changes. ESTs have been isolated from a wide variety of tissue libraries, particularly uterus, kidney, lung, tonsil and brain.Synonyms: C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, FB22, Fusin, HM89, LCR1, LESTR, Leukocyte-derived seven transmembrane domain receptor, NPYRL, SDF1 receptor, Stromal cell-derived factor 1 receptor

基因ID

7852

UniProt

P61073

途径

Regulation of Cell Size, CXCR4-mediated Signaling Events