Calcitonin Receptor 抗体
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Quick Overview for Calcitonin Receptor 抗体 (ABIN121621)
抗原
See all Calcitonin Receptor (CALCR) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- SP1338P reacts with the Calcitonin Receptor. It recognises an epitope within the cytoplasmic domain that is common to both C1a and C1b Rat isoforms.
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交叉反应 (详细)
- Species reactivity (tested):Rat. Cross reacts with Mouse and Human.
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纯化方法
- Affinity Chromatography on Protein A.
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免疫原
- Synthetic peptide derived from sequence of rat calcitonin receptor
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应用备注
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Immunohistochemistry on paraffin embedded tissues (1:10 - 1:100): The use of 4 % paraformaldehyde fixation rather than formalin fixation is recommended. Does not require protein digestion pre-treatment nor antigen retrieval using heat prior to staining of paraffin embedded sections. Suitable positive control: Kidney, cultered osteoclasts. A sensitive detection system is also recommended, e.g. a catalysed signal amplification system). ELISA (1:10,000). Western blot using reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.09 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. -
有效期
- 12 months
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: "Identification of the calcitonin receptor in osteoarthritic chondrocytes." in: BMC research notes, Vol. 4, pp. 407, (2011) (PubMed).
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: "Identification of the calcitonin receptor in osteoarthritic chondrocytes." in: BMC research notes, Vol. 4, pp. 407, (2011) (PubMed).
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- Calcitonin Receptor (CALCR)
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别名
- Calcitonin Receptor
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背景
- Calcitonin Receptor is a seven transmembrane domain cell surface protein which is coupled to G protein messenger systems. Calcitonin receptor is expressed in kidney, central and peripheral nervous systems and in osteoclasts. It is also expressed in a number of tissues during the development of the embyro and may be important in foetal morphogenesis.Synonyms: CALCR, CT-R, CTR
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基因ID
- 116506
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UniProt
- P32214
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途径
- cAMP Metabolic Process
抗原
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