GAD 抗体 (C-Term)
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Quick Overview for GAD 抗体 (C-Term) (ABIN121539)
抗原
See all GAD (GAD1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应 (详细)
- Also reacts to: GAD2 / GAD65
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产品特性
- Synonyms: Glutamate decarboxylase 1, GAD-67, Glutamate decarboxylase 67 kDa isoform, 67 kDaglutamic acid decarboxylase
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纯化方法
- Ammonium Sulphate Precipitation.
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免疫原
- Synthetic peptide sequence from the C-terminus of GADAA Sequence: D-F-L-I-E-E-I-E-R-L-G-Q-D-L
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应用备注
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ELISA. Western Blot: 1/1000-1/10000. Immunohistochemistry on Frozen Sections: 1/200-1/5000. Recommended Positive Control: Brain.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
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别名
- GAD1 / GAD67
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背景
- This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma aminobutyric acid from L glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin dependent diabetes. This gene may also play a role in the stiff man syndrome.Synonyms: 67 kDa glutamic acid decarboxylase, GAD-67, Glutamate decarboxylase 1, Glutamate decarboxylase 67 kDa isoform
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基因ID
- 2571
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UniProt
- Q99259
抗原
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