TUBA1B 抗体
Quick Overview for TUBA1B 抗体 (ABIN121117)
抗原
See all TUBA1B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- SM568P specifically recognizes the alpha subunit of Tubulin. The reactivity pattern is similar to that seen with Clone YL1/2 (cat.-No SM2202P). This antibody is routinely tested in ELISA on Tubulin.
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- Yeast tubulin
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亚型
- IgG2a
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应用备注
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Immunohistochemistry on Frozen Sections. ELISA: 10 μg/ul as detecting antibody. RIA. Western blotting.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This antibody is routinely tested in Elisa on Tubulin. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. -
有效期
- 12 months
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: "MicroRNA-15b regulates mitochondrial ROS production and the senescence-associated secretory phenotype through sirtuin 4/SIRT4. ..." in: Aging, Vol. 8, Issue 3, pp. 484-505, (2016) (PubMed).
: "Oral rice-based vaccine induces passive and active immunity against enterotoxigenic E. coli-mediated diarrhea in pigs." in: Vaccine, Vol. 33, Issue 39, pp. 5204-11, (2016) (PubMed).
: "Human cytomegalovirus infection interferes with major histocompatibility complex type II maturation and endocytic proteases in dendritic cells at multiple levels." in: The Journal of general virology, Vol. 89, Issue Pt 10, pp. 2427-36, (2008) (PubMed).
: "HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies." in: The EMBO journal, Vol. 25, Issue 11, pp. 2326-37, (2006) (PubMed).
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: "MicroRNA-15b regulates mitochondrial ROS production and the senescence-associated secretory phenotype through sirtuin 4/SIRT4. ..." in: Aging, Vol. 8, Issue 3, pp. 484-505, (2016) (PubMed).
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- TUBA1B (Tubulin, alpha 1B (TUBA1B))
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别名
- alpha Tubulin / TUBA1B
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背景
- Microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Tubulin itself is a globular protein consisting of two polypeptides (alpha and beta tubulin). Alpha and beta tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22-nm diameter. Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton-associated carboxypeptidase. Detyrosinated alpha tubulin is referred to as Glu-tubulin. Another post-translational modification of detyrosinated alpha tubulin is C-terminal polyglutamylation, which is characteristic of microtubules in neuronal cells and the mitotic spindle.Synonyms: Alpha-tubulin ubiquitous, Tubulin K-alpha-1, Tubulin alpha-1B chain, Tubulin alpha-ubiquitous chain
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途径
- Microtubule Dynamics, M Phase
抗原
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