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TUBA1B 抗体

This 大鼠 单克隆 antibody specifically detects TUBA1B in WB, IF, IHC (p), IHC (fro), IP, EIA 和 RIA. It exhibits reactivity toward 人, 小鼠, 大鼠, Avian, 哺乳动物 和 Saccharomyces cerevisiae. It has been mentioned in 4+ publications
产品编号 ABIN121117
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TUBA1B 抗体 (ABIN121117)

抗原

See all TUBA1B 抗体
TUBA1B (Tubulin, alpha 1B (TUBA1B))

适用

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人, 小鼠, 大鼠, Avian, 哺乳动物, Saccharomyces cerevisiae

宿主

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大鼠

克隆类型

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单克隆

标记

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This TUBA1B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Enzyme Immunoassay (EIA), Radioimmunoassay (RIA)

克隆位点

YOL1-34
  • 特异性

    SM568P specifically recognizes the alpha subunit of Tubulin. The reactivity pattern is similar to that seen with Clone YL1/2 (cat.-No SM2202P). This antibody is routinely tested in ELISA on Tubulin.

    纯化方法

    Affinity Chromatography on Protein G

    免疫原

    Yeast tubulin

    亚型

    IgG2a
  • 应用备注

    Immunohistochemistry on Frozen Sections. ELISA: 10 μg/ul as detecting antibody. RIA. Western blotting.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This antibody is routinely tested in Elisa on Tubulin.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf Life: one year from despatch.

    有效期

    12 months
  • Lang, Grether-Beck, Singh, Kuck, Jakob, Kefalas, Altinoluk-Hambüchen, Graffmann, Schneider, Lindecke, Brenden, Felsner, Ezzahoini, Marini, Weinhold, Vierkötter, Tigges, Schmidt, Stühler, Köhrer et al.: "MicroRNA-15b regulates mitochondrial ROS production and the senescence-associated secretory phenotype through sirtuin 4/SIRT4. ..." in: Aging, Vol. 8, Issue 3, pp. 484-505, (2016) (PubMed).

    Takeyama, Yuki, Tokuhara, Oroku, Mejima, Kurokawa, Kuroda, Kodama, Nagai, Ueda, Kiyono: "Oral rice-based vaccine induces passive and active immunity against enterotoxigenic E. coli-mediated diarrhea in pigs." in: Vaccine, Vol. 33, Issue 39, pp. 5204-11, (2016) (PubMed).

    Kessler, Reich, Jahn, Tolosa, Beck, Kalbacher, Overkleeft, Schempp, Driessen: "Human cytomegalovirus infection interferes with major histocompatibility complex type II maturation and endocytic proteases in dendritic cells at multiple levels." in: The Journal of general virology, Vol. 89, Issue Pt 10, pp. 2427-36, (2008) (PubMed).

    Valenta, Lukas, Doubravska, Fafilek, Korinek: "HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies." in: The EMBO journal, Vol. 25, Issue 11, pp. 2326-37, (2006) (PubMed).

  • 抗原

    TUBA1B (Tubulin, alpha 1B (TUBA1B))

    别名

    alpha Tubulin / TUBA1B

    背景

    Microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Tubulin itself is a globular protein consisting of two polypeptides (alpha and beta tubulin). Alpha and beta tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22-nm diameter. Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton-associated carboxypeptidase. Detyrosinated alpha tubulin is referred to as Glu-tubulin. Another post-translational modification of detyrosinated alpha tubulin is C-terminal polyglutamylation, which is characteristic of microtubules in neuronal cells and the mitotic spindle.Synonyms: Alpha-tubulin ubiquitous, Tubulin K-alpha-1, Tubulin alpha-1B chain, Tubulin alpha-ubiquitous chain

    途径

    Microtubule Dynamics, M Phase
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