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SOCS3 抗体

SOCS3 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 01-11-14 unconjugated
产品编号 ABIN120754
发货至: 中国
  • 抗原 See all SOCS3 抗体
    SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))
    适用
    • 45
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    • 1
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    宿主
    • 54
    • 16
    • 1
    小鼠
    克隆类型
    • 56
    • 15
    单克隆
    标记
    • 38
    • 11
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    • 3
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    This SOCS3 antibody is un-conjugated
    应用范围
    • 44
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody SO1 reacts with SOCS3, an intracellular Cytokine Signaling Inhibitor.
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Affinity Chromatography on Protein A
    免疫原
    Full-length SOCS3 protein
    克隆位点
    01-11-14
    亚型
    IgG2b
    Top Product
    Discover our top product SOCS3 Primary Antibody
  • 应用备注
    ELISA. Western blot: Use HeLa human cervix carcinoma cell line as positive control. Sample preparation: Resuspend approx. 50 mil. cells in 1 mLcold lysis buffer (1 % laurylmaltoside in 20 mM Tris/Cl, 100 mM NaCl pH 8.2, 50 mM NaF including protease inhibitor cocktail). Incubate 60 min on ice, centrifuge to remove cell debris. Mix lysate with reducing Laemmli SDS-PAGE sample buffer.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS with 15 mM Sodium Azide as preservative, approx. pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf Life: one year from despatch.
    有效期
    12 months
  • 抗原
    SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))
    别名
    SOCS3 / CIS3 (SOCS3 产品)
    别名
    socs3 antibody, fj09e12 antibody, zgc:56537 antibody, wu:fj09e12 antibody, MGC64393 antibody, MGC75749 antibody, xsocs3 antibody, MGC81248 antibody, atod4 antibody, cis3 antibody, cish3 antibody, socs-3 antibody, ssi-3 antibody, ssi3 antibody, SOCS3 antibody, ATOD4 antibody, CIS3 antibody, Cish3 antibody, SOCS-3 antibody, SSI-3 antibody, SSI3 antibody, Cis3 antibody, EF-10 antibody, Ef10 antibody, Ssi3 antibody, Socs-3 antibody, Ssi-3 antibody, suppressor of cytokine signaling 3a antibody, suppressor of cytokine signaling 3 S homeolog antibody, suppressor of cytokine signaling 3 antibody, suppressor of cytokine signaling 3 L homeolog antibody, socs3a antibody, socs3.S antibody, socs3 antibody, socs3.L antibody, SOCS3 antibody, Socs3 antibody
    背景
    SOCS3 (suppressor of cytokine signaling 3), also known as CIS3 (cytokine-inducible SH2 protein 3) is a negative regulator of particular cytokine signaling pathways. SOCS3 is induced by a variety of cytokines and other stimuli, such as erythropoietin, leptin and lipopolysaccharides and inhibits tyrosinkinase activity of JAK kinases, or e.g. JNK phosphorylation. SOCS3 modulates cytokine-mediated and neoplastic-proliferative responses and is involved also in maintaining leukocytes in quiescent state until antigen stimulation.Synonyms: CIS-3, Cytokine-inducible SH2 protein 3, SOCS-3, SSI-3, SSI3, STAT-induced STAT inhibitor 3, Suppressor of cytokine signaling 3
    基因ID
    9021
    UniProt
    O14543
    途径
    JAK/STAT Signaling, Response to Growth Hormone Stimulus, Hepatitis C
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