SOCS3 抗体
Quick Overview for SOCS3 抗体 (ABIN120754)
抗原
See all SOCS3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody SO1 reacts with SOCS3, an intracellular Cytokine Signaling Inhibitor.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Affinity Chromatography on Protein A
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免疫原
- Full-length SOCS3 protein
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亚型
- IgG2b
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anti-Suppressor of Cytokine Signaling 3 (SOCS3) (C-Term) antibody
SOCS3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-225) antibodySOCS3 适用: 人 ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E4 unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 155-225) antibodySOCS3 适用: 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (C-Term) antibodySOCS3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-224) antibodySOCS3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-226) antibodySOCS3 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1E4 unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) antibodySOCS3 适用: 人 WB 宿主: 小鼠 Monoclonal SO1 unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (C-Term) antibodySOCS3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 71-85), (Middle Region) antibodySOCS3 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-225) antibodySOCS3 适用: 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: Use HeLa human cervix carcinoma cell line as positive control. Sample preparation: Resuspend approx. 50 mil. cells in 1 mLcold lysis buffer (1 % laurylmaltoside in 20 mM Tris/Cl, 100 mM NaCl pH 8.2, 50 mM NaF including protease inhibitor cocktail). Incubate 60 min on ice, centrifuge to remove cell debris. Mix lysate with reducing Laemmli SDS-PAGE sample buffer.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS with 15 mM Sodium Azide as preservative, approx. pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. -
有效期
- 12 months
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- SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))
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别名
- SOCS3 / CIS3
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背景
- SOCS3 (suppressor of cytokine signaling 3), also known as CIS3 (cytokine-inducible SH2 protein 3) is a negative regulator of particular cytokine signaling pathways. SOCS3 is induced by a variety of cytokines and other stimuli, such as erythropoietin, leptin and lipopolysaccharides and inhibits tyrosinkinase activity of JAK kinases, or e.g. JNK phosphorylation. SOCS3 modulates cytokine-mediated and neoplastic-proliferative responses and is involved also in maintaining leukocytes in quiescent state until antigen stimulation.Synonyms: CIS-3, Cytokine-inducible SH2 protein 3, SOCS-3, SSI-3, SSI3, STAT-induced STAT inhibitor 3, Suppressor of cytokine signaling 3
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基因ID
- 9021
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UniProt
- O14543
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途径
- JAK/STAT Signaling, Response to Growth Hormone Stimulus, Hepatitis C
抗原
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