CD235a/GYPA 抗体 (N-Term)
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- 抗原 See all CD235a/GYPA (GYPA) 抗体
- CD235a/GYPA (GYPA) (Glycophorin A (GYPA))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD235a/GYPA antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Aggregation (AGG), Haemagglutination (H)
- 特异性
- This antibody clone HIR2 recognizes N-terminal portion of glycophorin A (and weakly of glycophorin B). Its antigen is expressed on early erythroblasts, late erythroblasts, erythroblasts, mature erythrocytes and the cells of erythroid cell lines K562 and HEL, but not on all other cells.
- 纯化方法
- Protein G chromatography
- 免疫原
- Synthetic peptide (Human, N-terminal)
- 克隆位点
- HIR2
- 亚型
- IgG2b
- Top Product
- Discover our top product GYPA Primary Antibody
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- 应用备注
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Flow cytometry: This HIR2 antibody has been tested by flow cytometric analysis of human peripheral blood leukocytes and cell agglutination assay and can be used at approximately 0.1 μg per million cells. Immunohistochemistry (frozen sections). Agglutination: Clone HIR2 agglutinates untreated RBCs but it failes to agglutinate papain- treated cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS with 15 mM sodium azide, approx. pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. - 有效期
- 12 months
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ImmunoPEGliposomes for the targeted delivery of novel lipophilic drugs to red blood cells in a falciparum malaria murine model." in: Biomaterials, Vol. 145, pp. 178-191, (2018) (PubMed).
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ImmunoPEGliposomes for the targeted delivery of novel lipophilic drugs to red blood cells in a falciparum malaria murine model." in: Biomaterials, Vol. 145, pp. 178-191, (2018) (PubMed).
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- 抗原
- CD235a/GYPA (GYPA) (Glycophorin A (GYPA))
- 别名
- CD235a / GYPA (GYPA 产品)
- 别名
- GYPA antibody, gpa antibody, AI853584 antibody, CD235a antibody, GPA antibody, GPErik antibody, GPSAT antibody, HGpMiV antibody, HGpMiXI antibody, HGpSta(C) antibody, MN antibody, MNS antibody, PAS-2 antibody, glycophorin A (MNS blood group) antibody, glycophorin A antibody, GYPA antibody, Gypa antibody
- 背景
- CD235a (Glycophorin A, GPA) is a transmembrane sialoglycoprotein expressed on erythrocytes and their precursors. Similarly to glycophorin B (GPB), these molecules provide the cells with a large mucin-like surface, which minimalizes aggregation between erythrocytes in the circulation. GPA is the carrier of blood group M and N specificities, while GPB accounts for S, s and U specificities. CD235a is a receptor of Hsa, an Streptococcus adhesin.Synonyms: GPA, Glycophorin-A, MN sialoglycoprotein, PAS-2, Sialoglycoprotein alpha
- 基因ID
- 2993
- UniProt
- P02724
- 途径
- Maintenance of Protein Location
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