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MHC Class I RT1.Aa alpha-Chain (RT1.AA) 抗体

This 小鼠 单克隆 antibody specifically detects MHC Class I RT1.Aa alpha-Chain in FACS, IHC (fro) 和 IP. It exhibits reactivity toward 大鼠.
产品编号 ABIN120718
发货至: 中国
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Quick Overview for MHC Class I RT1.Aa alpha-Chain (RT1.AA) 抗体 (ABIN120718)

抗原

See all MHC Class I RT1.Aa alpha-Chain (RT1.AA) 抗体
MHC Class I RT1.Aa alpha-Chain (RT1.AA)

适用

大鼠

宿主

  • 1
小鼠

克隆类型

  • 1
单克隆

标记

  • 1
非结合性

应用范围

Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)

克隆位点

OX-18
  • 纯化方法

    Protein G Chromotraphy

    免疫原

    Rat spleen membrane glycoproteins depleted of Ia-A antigens. Donor: BALB/c spleen. Fusion Partner: X63 Ag8.653

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS

    储存液

    Azide free

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Handle under aseptic conditions.
    Shelf Life: one year from despatch.

    有效期

    12 months
  • 抗原

    MHC Class I RT1.Aa alpha-Chain (RT1.AA)

    别名

    MHC Class I (RT1Aa)

    背景

    MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44 kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.Synonyms: RT1 class I histocompatibility antigen AA alpha chain
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