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CD8 抗体 (PE)

CD8 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-31 PE
产品编号 ABIN120697
发货至: 中国
  • 抗原 See all CD8 抗体
    CD8
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD8 antibody is conjugated to PE
    应用范围
    • 276
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    Flow Cytometry (FACS)
    特异性
    The antibody recognizes a conformationally-dependent epitope of CD8 antigen.
    产品特性
    Synonyms: T-lymphocyte differentiation antigen T8/Leu-2, T-cell surface glycoprotein CD8 alpha chain
    免疫原
    Crude thymus membrane fraction.
    克隆位点
    MEM-31
    亚型
    IgG2a
    Top Product
    Discover our top product CD8 Primary Antibody
  • 应用备注
    Flow Cytometry analysis of human blood cells using 20 l reagent / 100 l whole blood or10^6 cells in a suspension. Does not work in Immunohistocchemistry omn paraffin sections or Western blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    储存条件
    4 °C
    储存方法
    Store at 2-8 °C. Do not freeze. Avoid prolonged exposure to light.
    Shelf life: one year fromdespatch.
    有效期
    12 months
  • 抗原
    CD8
    别名
    CD8 (CD8 产品)
    背景
    The CD8 T cell coreceptor (monomer approx. 32-34 kDa) is expressed as ab heterodimer on majority of MHC I-restricted conventional T cells and thymocytes and as aa homodimer on subsets of memory T cells, intraepithelial lymphocytes, NK cells and dendritic cells. Regulation of CD8b level on T cell surface seems to be an important mechanism to control their effector function. Assembly of CD8 a-b but not a-a dimers is connected with formation or localization to the lipid rafts. Recruiting triggered TCR complexes to these membrane microdomains as well as affinity of TCR to MHC I is modulated by CD8, thereby affecting the functional diversity of the TCR signaling.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
    基因ID
    925
    UniProt
    P01732
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