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CD8 抗体 (PE)

This anti-CD8 antibody is a 小鼠 单克隆 antibody detecting CD8 in FACS. Suitable for 人.
产品编号 ABIN120697
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD8 抗体 (PE) (ABIN120697)

抗原

See all CD8 抗体
CD8

适用

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宿主

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小鼠

克隆类型

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单克隆

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This CD8 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

MEM-31
  • 特异性

    The antibody recognizes a conformationally-dependent epitope of CD8 antigen.

    产品特性

    Synonyms: T-lymphocyte differentiation antigen T8/Leu-2, T-cell surface glycoprotein CD8 alpha chain

    免疫原

    Crude thymus membrane fraction.

    亚型

    IgG2a
  • 应用备注

    Flow Cytometry analysis of human blood cells using 20 l reagent / 100 l whole blood or10^6 cells in a suspension. Does not work in Immunohistocchemistry omn paraffin sections or Western blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    储存条件

    4 °C

    储存方法

    Store at 2-8 °C. Do not freeze. Avoid prolonged exposure to light.
    Shelf life: one year fromdespatch.

    有效期

    12 months
  • 抗原

    CD8

    别名

    CD8

    背景

    The CD8 T cell coreceptor (monomer approx. 32-34 kDa) is expressed as ab heterodimer on majority of MHC I-restricted conventional T cells and thymocytes and as aa homodimer on subsets of memory T cells, intraepithelial lymphocytes, NK cells and dendritic cells. Regulation of CD8b level on T cell surface seems to be an important mechanism to control their effector function. Assembly of CD8 a-b but not a-a dimers is connected with formation or localization to the lipid rafts. Recruiting triggered TCR complexes to these membrane microdomains as well as affinity of TCR to MHC I is modulated by CD8, thereby affecting the functional diversity of the TCR signaling.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2

    基因ID

    925

    UniProt

    P01732
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