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CD1a 抗体 (FITC)

CD1a 适用: 人 FACS 宿主: 小鼠 Monoclonal HI149 FITC
产品编号 ABIN120677
发货至: 中国
  • 抗原 See all CD1a 抗体
    CD1a
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    小鼠
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    单克隆
    标记
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    This CD1a antibody is conjugated to FITC
    应用范围
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    Flow Cytometry (FACS)
    特异性
    The antibody reacts with CD1a (T6), a 49 KDa polypeptide associated with, b2-microglobulin expressed on cortical thymocytes (strongly), Langerhans cells, dendritic cells and some T cell leukemias and lymphomas. The antibody does not react with peripheral blood T and B lymphocytes, monocytes, granulocytes, platelets and erythrocytes.
    免疫原
    Human thymocytes
    克隆位点
    HI149
    亚型
    IgG1
    Top Product
    Discover our top product CD1a Primary Antibody
  • 应用备注
    Flow Cytometry analysis of human cells using 20 μL reagent / 100 mLof whole blood or 10^6 cells in a suspension.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
    Shelf Life: one year from despatch.
    有效期
    12 months
  • 抗原
    CD1a
    别名
    CD1a (CD1a 产品)
    背景
    CD1a, together with CD1b and c, belongs to group 1 of CD1 glycoproteins. These proteins serve as antigen-presenting molecules for a subset of T cells that responds to specific lipids and glycolipids found in the cell walls of bacterial pathogens or self-glycolipid antigens such as gangliosides, and they have also roles in antiviral immunity. Unlike CD1b, CD1a is excluded from late endosomal compartments and instead traffics independently in the recycling pathway of the early endocytic system, and CD1a antigen presentation is independent upon vesicular acidification.Synonyms: T-cell surface antigen T6/Leu-6, T-cell surface glycoprotein CD1a, T6/Leu-6, hTa1, hTa1 thymocyte antigen
    UniProt
    P06126
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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