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CD52 抗体

This anti-CD52 antibody is a 小鼠 单克隆 antibody detecting CD52 in FACS, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN120666
发货至: 中国

Quick Overview for CD52 抗体 (ABIN120666)

抗原

See all CD52 抗体
CD52

适用

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宿主

  • 33
  • 25
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小鼠

克隆类型

  • 74
  • 6
  • 3
单克隆

标记

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This CD52 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

HI186
  • 特异性

    This antibody Clone HI186 reacts with CD52, a 25-29 kDa glycoprotein containing a large N-linked carbohydrate moiety. Mature CD52 Molecule is actually much smaller (approx. 8-9 kDa).

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Protein A Chromatography

    免疫原

    Human tonsil

    亚型

    IgG2b
  • 应用备注

    Flow cytometry: use 5 μL of neat antibody to label 10^6 cells. Immunohistochemistry on frozen and paraffin embedded sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH ~7.4, 15 mM Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2-8 °C for up to one month or at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf Life: one year from despatch.

    有效期

    12 months
  • 抗原

    CD52

    别名

    CD52 / CAMPATH-1

    背景

    CD52 (CAMPATH-1, HE5) is a highly glycosylated GPI-anchored 21-28 kDa glycopeptide which is present at high levels on lymphocytes, macrophages, epithelial cells of male reproductive tract and mature sperm. Its 12-amino acid beckbone carries a complex N-linked carbohydrate moiety, which differs between sperm and leukocyte CD52, as well as the GPI anchor does. CD52 can be acquired by sperm cells from seminal plasma, where it is released by epithelial cells. Although CD52 is not an essential T-cell costimulator, its triggering results in activation of normal human T cells. CD52 is a very good target for antibody/complement-mediated cell lysis.Synonyms: CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, HE5

    基因ID

    1043

    UniProt

    P31358
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