CD9 抗体
Quick Overview for CD9 抗体 (ABIN120621)
抗原
See all CD9 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- The antibody recognizes an epitope on second extracellular domain (EC2) of CD9 antigen, a 24 kDa single transmembrane polypeptide expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes.
-
纯化方法
- Affinity Chromatography on Protein A
-
免疫原
- Pre-B cell line NALM-6
-
亚型
- IgG1
-
-
-
-
应用备注
-
Immunohistochemistry (paraffin sections): Recommended dilution: 20 m g/mL, Positive tissue: prostate. Flow cytometry. Immunoprecipitation. Western Blotting (non reducing conditions). Functional Application (The antibody induces FcgR-dependent platelet activation / aggregation).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Phosphate buffered saline (PBS), pH ~7.4 with 15 mM Sodium Azide as preservative
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C/-20 °C
-
储存方法
-
Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. -
有效期
- 12 months
-
-
- CD9
-
别名
- CD9
-
背景
- CD9 belongs to proteins of tetraspanin family that orchestrate cholesterol-associated tetraspanin-enriched signaling microdomains within the plasma membrane, forming complexes with each other as well as with integrins, membrane-anchored growth factors and other proteins. CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 is also considered as metastasis suppressor in solid tumors.Synonyms: 5H9 antigen, Cell growth-inhibiting gene 2 protein, GIG2, Leukocyte antigen MIC3, MIC3, Motility-related protein, TSPAN29, Tetraspanin-29, p24
-
基因ID
- 928
-
UniProt
- P21926
-
途径
- Response to Water Deprivation, Cell-Cell Junction Organization
抗原
-