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ICAM-3/CD50 抗体

ICAM3 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal MEM-171 unconjugated
产品编号 ABIN120603
发货至: 中国
  • 抗原 See all ICAM-3/CD50 (ICAM3) 抗体
    ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
    适用
    • 110
    • 3
    • 2
    • 2
    宿主
    • 67
    • 42
    • 1
    小鼠
    克隆类型
    • 70
    • 40
    单克隆
    标记
    • 59
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    • 3
    • 2
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    This ICAM-3/CD50 antibody is un-conjugated
    应用范围
    • 60
    • 49
    • 45
    • 34
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    • 7
    • 7
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    Flow Cytometry (FACS), Immunoprecipitation (IP)
    特异性
    The antibody recognizes an epitope in the D2 domain of human CD50 (ICAM-3).
    纯化方法
    Protein-A affinity chromatography
    纯度
    > 95 % pure (by SDS-PAGE)
    免疫原
    Humangranulocytes
    克隆位点
    MEM-171
    亚型
    IgG1
    Top Product
    Discover our top product ICAM3 Primary Antibody
  • 应用备注
    Flow cytometry. Immunoprecipitation.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 4-8 °C for up to one month or at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf Life: one year from despatch.
    有效期
    12 months
  • 抗原
    ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
    别名
    CD50 / ICAM3 (ICAM3 产品)
    别名
    CD50 antibody, CDW50 antibody, ICAM-R antibody, ICAM-3 antibody, ICAM3 antibody, intercellular adhesion molecule 3 antibody, ICAM3 antibody, Icam3 antibody
    背景
    CD50 is a transmembrane glycoprotein expressed by leukocytes, that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin. Besides functioning as an adhesive molecule that mediates e.g. the contact between T cells and antigen presenting cells, ICAM-3 regulates affinity of LFA-1 for ICAM-1 and induces T cell activation and proliferation. ICAM-3 plays an essential role in the initiation of the immune response both on T cells and antigen presenting cells and interacts also with CD209 (dendritic cell-specific ICAM-3-grabbing nonintegrin, DC-SIGN), a C-type lectin of dendritic cells and macrophages, this process is involved in dialogue between dendritic cells and granulocytes.Synonyms: CDw50, ICAM-3, ICAM-R, Intercellular adhesion molecule 3
    基因ID
    3385
    UniProt
    P32942
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