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ICAM-3/CD50 抗体

This anti-ICAM-3/CD50 antibody is a 小鼠 单克隆 antibody detecting ICAM-3/CD50 in FACS 和 IP. Suitable for 人.
产品编号 ABIN120603
发货至: 中国

Quick Overview for ICAM-3/CD50 抗体 (ABIN120603)

抗原

See all ICAM-3/CD50 (ICAM3) 抗体
ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))

适用

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宿主

  • 101
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小鼠

克隆类型

  • 114
  • 33
单克隆

标记

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This ICAM-3/CD50 antibody is un-conjugated

应用范围

  • 93
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Flow Cytometry (FACS), Immunoprecipitation (IP)

克隆位点

MEM-171
  • 特异性

    The antibody recognizes an epitope in the D2 domain of human CD50 (ICAM-3).

    纯化方法

    Protein-A affinity chromatography

    纯度

    > 95 % pure (by SDS-PAGE)

    免疫原

    Humangranulocytes

    亚型

    IgG1
  • 应用备注

    Flow cytometry. Immunoprecipitation.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 4-8 °C for up to one month or at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf Life: one year from despatch.

    有效期

    12 months
  • 抗原

    ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))

    别名

    CD50 / ICAM3

    背景

    CD50 is a transmembrane glycoprotein expressed by leukocytes, that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin. Besides functioning as an adhesive molecule that mediates e.g. the contact between T cells and antigen presenting cells, ICAM-3 regulates affinity of LFA-1 for ICAM-1 and induces T cell activation and proliferation. ICAM-3 plays an essential role in the initiation of the immune response both on T cells and antigen presenting cells and interacts also with CD209 (dendritic cell-specific ICAM-3-grabbing nonintegrin, DC-SIGN), a C-type lectin of dendritic cells and macrophages, this process is involved in dialogue between dendritic cells and granulocytes.Synonyms: CDw50, ICAM-3, ICAM-R, Intercellular adhesion molecule 3

    基因ID

    3385

    UniProt

    P32942
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