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CD34 抗体 (FITC)

This anti-CD34 antibody is a 小鼠 单克隆 antibody detecting CD34 in FACS. Suitable for 人.
产品编号 ABIN120582
发货至: 中国

Quick Overview for CD34 抗体 (FITC) (ABIN120582)

抗原

See all CD34 抗体
CD34

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD34 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

4H11
  • 特异性

    The antibody reacts with Class III epitope on CD34 (Mucosialin), a 110-115 kDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells, it is gradually lost on progenitor cells. The antibody completely blocks binding of Class II antibody QBEnd10 and Class III antibodies BIRMA K3 and 8G12 on KG1a cell line.

    免疫原

    Permanent human cell line derived from peripheral leucocytes of a patient suffering from chronic myeloid leukaemia

    亚型

    IgG1
  • 应用备注

    Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL sample. Note: This conjugate is routinely tested on permanent CML cell line MOLM-7.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 15 mM Sodium Azide as preservative and 0.2 % (w/v) high-grade protease free BSA as a stabilizing agent.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
    Shelf Life: one year from despatch.

    有效期

    12 months
  • 抗原

    CD34

    别名

    CD34

    背景

    CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.Synonyms: Hematopoietic progenitor cell antigen CD34, Hematopoietic progenitor cell marker

    基因ID

    947

    UniProt

    P28906
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