ITGAL 抗体 (Biotin)
Quick Overview for ITGAL 抗体 (Biotin) (ABIN120404)
抗原
See all ITGAL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This Antibody is specific for the a subunit of LFA-1. It inhibits homeotypic aggregation of PHA blasts and blocks the binding of rat lymphocytes to purified rat ICAM-1.
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免疫原
- Rat Splenic PHA blasts Donor: BALB/c spleen Fusion Partner: Mouse myeloma cell line PAI
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亚型
- IgG2a
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应用备注
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Immunoprecipitation. Flow cytometry. Immunohistochemistry (cryostat sections). Functional studies: in vivo/in vitro
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.09 % NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ITGAL (Integrin alpha-L (ITGAL))
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别名
- CD11a / ITGAL
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背景
- LFA-1 (lymphocyte function associated molecule-1) is one of the leukocyte integrins. It is a heterodimer consisting of a and b subunits of 160-170 kDa and 95-100 kDa respectively. LFA-1 promotes non-antigen dependent adhesion of T-cells to a variety of lymphoid cells that bear its complementary receptor I-CAM-1 (1). It has a broad distribution and is found on most common lymphocytes.Synonyms: CD11 antigen-like family member A, Integrin alpha-L, LFA-1, LFA1, Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte function-associated molecule 1 alpha chain
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基因ID
- 308995
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NCBI登录号
- NP_001029170
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UniProt
- Q3T1L6
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途径
- Activated T Cell Proliferation, Integrin Complex
抗原
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