CD2 抗体
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北京 101111
Quick Overview for CD2 抗体 (ABIN120363)
抗原
See all CD2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognises the CD2 cell surface antigen, a 50-54 kDa glycoprotein expressed by thymocytes and mature T cells.
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纯化方法
- Affinity chromatography on Protein G
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免疫原
- Activated rat T helper cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
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亚型
- IgG2a
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应用备注
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Flow cytometry: 1/50, use 10 μL of the suggested working dilution to label 106 cells in 100 μL. Immunoprecipitation. Immunohistochemistry on frozen sections and paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CD2
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别名
- CD2
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背景
- CD2 is a surface antigen of the human T lymphocyte lineage that is expressed on all peripheral blood T cells. It is one of the earliest T cell markers, being present on more than 95 % of thymocytes, it is also found on some natural killer cells but not on B lymphocytes. CD2 interacts with lymphocyte function associated antigen (LFA3) and CD48/BCM1 to mediate adhesion between T cells and other cell types. CD2 is implicated in the triggering of T cells, the cytoplasmic domain is implicated in the signaling function. It is useful for the identification of lymphomas and leukaemias of T cell origin.Synonyms: Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, SRBC, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5
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基因ID
- 497761
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NCBI登录号
- NP_036962
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UniProt
- P08921
抗原
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