CD2 抗体
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- 抗原 See all CD2 抗体
- CD2
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD2 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- This monoclonal antibody reacts with the 50 kDa surface glycoprotein LFA-2, designated as CD2. LFA-2 is the receptor for LFA-3. This antibody labels all peripheral T cells and most thymocytes but does not label B cells or peritoneal macrophages. It does not activate T cells.
- 纯化方法
- Protein G Chromatography
- 免疫原
- T blasts prepared in mixed lymphocyte reactions with purified rat T helper cells against irradiated spleen. Donor: BALB/c spleen Fusion Partner: NSO/1
- 克隆位点
- OX-34
- 亚型
- IgG2a
- Top Product
- Discover our top product CD2 Primary Antibody
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- 应用备注
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Immunohistochemistry on frozen and paraffin sections. Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS,no preservative.
- 储存液
- Without preservative
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- CD2
- 别名
- CD2 (CD2 产品)
- 背景
- CD2 is a surface antigen of the human T lymphocyte lineage that is expressed on all peripheral blood T cells. It is one of the earliest T cell markers, being present on more than 95 % of thymocytes, it is also found on some natural killer cells but not on B lymphocytes. CD2 interacts with lymphocyte function associated antigen (LFA3) and CD48/BCM1 to mediate adhesion between T cells and other cell types. CD2 is implicated in the triggering of T cells, the cytoplasmic domain is implicated in the signaling function. It is useful for the identification of lymphomas and leukaemias of T cell origin.Synonyms: Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, SRBC, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5
- 基因ID
- 497761
- NCBI登录号
- NP_036962
- UniProt
- P08921
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