CD2 抗体
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北京 101111
Quick Overview for CD2 抗体 (ABIN120360)
抗原
See all CD2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This monoclonal antibody reacts with the 50 kDa surface glycoprotein LFA-2, designated as CD2. LFA-2 is the receptor for LFA-3. This antibody labels all peripheral T cells and most thymocytes but does not label B cells or peritoneal macrophages. It does not activate T cells.
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纯化方法
- Protein G Chromatography
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免疫原
- T blasts prepared in mixed lymphocyte reactions with purified rat T helper cells against irradiated spleen. Donor: BALB/c spleen Fusion Partner: NSO/1
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亚型
- IgG2a
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应用备注
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Immunohistochemistry on frozen and paraffin sections. Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS,no preservative.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CD2
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别名
- CD2
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背景
- CD2 is a surface antigen of the human T lymphocyte lineage that is expressed on all peripheral blood T cells. It is one of the earliest T cell markers, being present on more than 95 % of thymocytes, it is also found on some natural killer cells but not on B lymphocytes. CD2 interacts with lymphocyte function associated antigen (LFA3) and CD48/BCM1 to mediate adhesion between T cells and other cell types. CD2 is implicated in the triggering of T cells, the cytoplasmic domain is implicated in the signaling function. It is useful for the identification of lymphomas and leukaemias of T cell origin.Synonyms: Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, SRBC, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5
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基因ID
- 497761
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NCBI登录号
- NP_036962
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UniProt
- P08921
抗原
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