P-Selectin 抗体
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- 抗原 See all P-Selectin (SELP) 抗体
- P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
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适用
- 人, 小鼠, 大鼠, 绵羊, Cow, 山羊, 马, Cat
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This P-Selectin antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- This antibody recognises the CD62P cell surface antigen.
- 纯化方法
- Affinity Chromatography on Protein G
- 免疫原
- P-selectin transfected 300.19 cells. Remarks: Spleen cells from immunised CD62P knock-out mice (strain C57/B6) were fused with cells of the NS-1 myeloma cell line.
- 克隆位点
- Psel-KO-2-7
- 亚型
- IgG1
- Top Product
- Discover our top product SELP Primary Antibody
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anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (AA 701-768) antibody
SELP 适用: 人, 小鼠, 大鼠, Pig WB, FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (AA 198-432) antibodySELP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (AA 58-158) antibodySELP 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) antibodySELP 适用: 人, Non-Human Primate WB, FACS, IP, ICC 宿主: 小鼠 Monoclonal AK4 unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (AA 30-200) antibodySELP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (AA 58-195) antibodySELP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) antibodySELP 适用: 人, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) antibodySELP 适用: 人, Non-Human Primate WB, FACS, IP, ICC, Func 宿主: 小鼠 Monoclonal AK4 unconjugated
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) antibody (Biotin)SELP 适用: 人, Non-Human Primate WB, FACS, IP, ICC 宿主: 小鼠 Monoclonal AK4 Biotin
anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (N-Term) antibodySELP 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Flow Cytometry: Use 10 μL of 1/25-1/50 diluted antibody to label 10^6 cells in 100 μL. Immunohistology on Frozen Sections (1/200, see reference 1). Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
- 别名
- CD62P / P-Selectin (SELP 产品)
- 别名
- PSELECT antibody, CD62 antibody, CD62P antibody, GMP140 antibody, GRMP antibody, LECAM3 antibody, PADGEM antibody, PSEL antibody, GMP-140 antibody, Grmp antibody, selectin P antibody, selectin, platelet antibody, Selp antibody, SELP antibody
- 背景
- CD62P is a 140 kD glycoprotein expressed by activated platelets and endothelial cells. It plays an important role in adhesive processes between leucocytes and endothelial cells. CD62P is a member of the small selectin family of cellular adhesion molecules, which also includes CD62E and CD62L. Its structure, similar to the other members of the selectin family, consists of an N terminal lectin like domain of C type, followed by an epidermal growth factor like motif, a series of short consensus repeats, a transmembrane domain, and a cytoplasmic tail. The CD62P antigen is a 140 kDa glycoprotein, located in the alpha granules and the dense granules of platelets and endothelial cells. Activation of these cells results in rapid mobilization of CD62P from the storage granules to the cell surface. Activated platelets have a stable CD62P expression, while the endothelial cells lose CD62P expression within 1 h of activation, because of endocytosis of the molecule. CD62P is also expressed on megakaryocytes, but resting platelets and endothelial cells show no surface staining of CD62P.Synonyms: CD62 antigen-like family member P, GMP-140, GMRP, GRMP, Granule membrane protein 140, LECAM3, Leukocyte-endothelial cell adhesion molecule 3, PADGEM, SELP
- 基因ID
- 6403
- NCBI登录号
- NP_002996
- UniProt
- P16109
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