Fc epsilon RI/FCER1A 抗体
Quick Overview for Fc epsilon RI/FCER1A 抗体 (ABIN120271)
抗原
See all Fc epsilon RI/FCER1A (FCER1A) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- SM2251P recognises the high affinity Fc receptor for IgE (Fc epsilon R1), which plays a central role in the IgE-mediated allergic response. Clone 9E1 specifically recognises the extracellular D1 domain of the Fc epsilon R1 alpha chain.
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- CCR7 Rat basophilic leukaemia (RBL)-2H3 transfectants. Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0-Ag14 myeloma cell line.
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亚型
- IgG2b
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应用备注
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ELISA. Western Blot. Immunoprecipitation. Immunofluorescence. Flow Cytometry: 1/25 - 1/50, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4, 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
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别名
- FCER1A
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背景
- Fc epsilon R1 consists of four subunits, a high affinity IgE binding alpha subunit, a beta chain and two di-sulphide linked gamma subunits. Fc epsilon R1 is primarily expressed on mast cells and basophils but expression of Fc epsilon R1 has also been reported on monocytes, Langerhans cells and dendritic cells from patients with atopic diseases.Synonyms: FCE1A, Fc-epsilon RI-alpha, FcERI, High affinity immunoglobulin epsilon receptor subunit alpha, IgE Fc receptor subunit alpha
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基因ID
- 2205
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NCBI登录号
- NP_001992
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UniProt
- P12319
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途径
- Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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