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NCR1 抗体 (PE)

This anti-NCR1 antibody is a 小鼠 单克隆 antibody detecting NCR1 in FACS. Suitable for Cow.
产品编号 ABIN120215
发货至: 中国

Quick Overview for NCR1 抗体 (PE) (ABIN120215)

抗原

See all NCR1 抗体
NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

适用

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Cow

宿主

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小鼠

克隆类型

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单克隆

标记

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This NCR1 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

AKS1
  • 特异性

    This antibody is specific for CD335, also known as NKp46 and Natural cytotoxicity triggering receptor 1. Clone AKS1 is reported to activate lysis of FcgammaR-expressing cell line P815, by IL-2 activated NKp46+ cells.

    纯化方法

    Affinity Chromatography on Protein G.

    免疫原

    Fusion protein consisting of the extracellular region of bovine CD335. Spleen cells from immunised Balb/c mice were fused with cells of the NS-0 myeloma cell line.

    亚型

    IgG1
  • 应用备注

    Flow Cytometry: neat- 1/5, use 10 μL of the suggested working dilution to label 106 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with 1 mL distilled water

    浓度

    0.1 mg/mL

    缓冲液

    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Lyophilized and reconstituted antibody ist stable at 2 - 8 °C for up to one month or at -20 °C for longer.
  • 抗原

    NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

    别名

    CD335 / NKp46

    背景

    CD335 is a type I transmembrane protein, with two extracellular C2-type immunoglobulin-like domains, which functions as an activating receptor. CD335 is primarily expressed by a subset natural killer (NK) cells. No expression of CD335 has been detected on B cells, T cells, monocytes or granulocytes.Synonyms: LY94, NCR1, NK cell-activating receptor, NKp46, Natural cytotoxicity triggering receptor, Natural killer cell p46-related protei

    基因ID

    369024

    NCBI登录号

    NP_899209

    UniProt

    Q863H2

    途径

    Regulation of Leukocyte Mediated Immunity
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