NCR1 抗体 (PE)
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Quick Overview for NCR1 抗体 (PE) (ABIN120215)
抗原
See all NCR1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody is specific for CD335, also known as NKp46 and Natural cytotoxicity triggering receptor 1. Clone AKS1 is reported to activate lysis of FcgammaR-expressing cell line P815, by IL-2 activated NKp46+ cells.
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纯化方法
- Affinity Chromatography on Protein G.
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免疫原
- Fusion protein consisting of the extracellular region of bovine CD335. Spleen cells from immunised Balb/c mice were fused with cells of the NS-0 myeloma cell line.
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亚型
- IgG1
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应用备注
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Flow Cytometry: neat- 1/5, use 10 μL of the suggested working dilution to label 106 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with 1 mL distilled water
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Lyophilized and reconstituted antibody ist stable at 2 - 8 °C for up to one month or at -20 °C for longer.
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- NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
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别名
- CD335 / NKp46
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背景
- CD335 is a type I transmembrane protein, with two extracellular C2-type immunoglobulin-like domains, which functions as an activating receptor. CD335 is primarily expressed by a subset natural killer (NK) cells. No expression of CD335 has been detected on B cells, T cells, monocytes or granulocytes.Synonyms: LY94, NCR1, NK cell-activating receptor, NKp46, Natural cytotoxicity triggering receptor, Natural killer cell p46-related protei
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基因ID
- 369024
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NCBI登录号
- NP_899209
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UniProt
- Q863H2
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途径
- Regulation of Leukocyte Mediated Immunity
抗原
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