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ITGB1 抗体

ITGB1 适用: 小鼠, 大鼠 FACS, IP, Func 宿主: 仓鼠 Monoclonal HM beta 1-1 unconjugated
产品编号 ABIN120158
发货至: 中国
  • 抗原 See all ITGB1 抗体
    ITGB1 (Integrin beta 1 (ITGB1))
    适用
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    小鼠, 大鼠
    宿主
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    仓鼠
    克隆类型
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    单克隆
    标记
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    This ITGB1 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)
    特异性
    This antibody recognises the integrin beta 1 subunit (CD29). Clone HM beta 1.1 is reported to inhibit beta 1 integrin mediated adhesion.
    纯化方法
    Affinity Chromatography on Protein G.
    内毒素水平
    Low Endotoxin
    免疫原
    Purified mouse VLA-4 antigen. Spleen cells from immunised Armenian hamsters were fused with cells of the P3U1 mouse myeloma cell line.
    克隆位点
    HM beta 1-1
    亚型
    IgG
    Top Product
    Discover our top product ITGB1 Primary Antibody
  • 应用备注
    Flow Cytometry (1/50-1/100): Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunoprecipitation. Functional Assays.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Endotoxin Level: less than 0.01 EU/mg.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS without preservatives.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • 抗原
    ITGB1 (Integrin beta 1 (ITGB1))
    别名
    CD29 / Integrin beta-1 (ITGB1 产品)
    背景
    CD29 is a 110 kDa cell surface glycoprotein that is widely expressed by a variety of cells including all leucocytes. CD29 forms non-covalent bonds with the integrin alpha subunits, including CD51 and CD49a-f, to form heterodimers. The ligands for these heterodimers include collagen, fibronectin, laminin and vascular adhesion molecule-1. In the immune system beta 1 integrins play an important role in cell adhesion, migration, activation and differentiation.Synonyms: FNRB, Fibronectin receptor subunit beta, ITGB1, Integrin VLA-4 subunit beta, MDF2, MSK12
    基因ID
    16412
    NCBI登录号
    NP_034708
    UniProt
    P09055
    途径
    Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome
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