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ITGA4 抗体

ITGA4 适用: 小鼠 FACS, IHC (fro) 宿主: 大鼠 Monoclonal 9C10 (MFR-4-B) unconjugated
产品编号 ABIN119961
发货至: 中国
  • 抗原 See all ITGA4 抗体
    ITGA4 (Integrin alpha 4 (ITGA4))
    适用
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    小鼠
    宿主
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    大鼠
    克隆类型
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    单克隆
    标记
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    This ITGA4 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody recognises alpha 4 integrin (CD49d). Clone 9C10 (MFR4.B) is reported to significantly inhibit binding of CD49d to CD106 but only when used in combination with clone R1-2.
    纯化方法
    Affinity chromatography on Protein G
    免疫原
    Mouse LyD9 haematopoietic progenitor cells. Spleen cells from immunised Lewis rats were fused with cells of the mouse P3X63Ag8.653 myeloma cell line.
    克隆位点
    9C10 (MFR-4-B)
    亚型
    IgG2a
    Top Product
    Discover our top product ITGA4 Primary Antibody
  • 应用备注
    Flow Cytometry: 1/10 - 1/5, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunohistochemistry on frozen sections. Removal of sodium azide is recommended prior to use in functional assays.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.4 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ITGA4 (Integrin alpha 4 (ITGA4))
    别名
    CD49d / ITGA4 (ITGA4 产品)
    别名
    CD49D antibody, IA4 antibody, LOC100219853 antibody, integrin subunit alpha 4 antibody, integrin alpha 4 antibody, integrin subunit alpha 4 S homeolog antibody, ITGA4 antibody, Itga4 antibody, itga4.S antibody
    背景
    CD49d is a 150kD glycoprotein that can associate with either beta 1 integrin (CD29) or beta 7 integrin to form heterodimers CD49d/CD29 (VLA-4) and alpha4/beta7 (LPAM-1) respectively. CD49d is expressed on most lymphocytes, granulocytes, monocytes and thymocytes. The primary ligands for CD49d are CD106 (VCAM-1), fibronectin and MAdCAM-1.Synonyms: CD49 antigen-like family member D, Integrin alpha-4, Integrin alpha-IV, VLA-4, VLA4
    基因ID
    16401
    NCBI登录号
    NP_034706
    UniProt
    Q00651
    途径
    Integrin Complex
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