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ITGA4 抗体 (FITC)

The FITC-conjugated 大鼠 单克隆 anti-ITGA4 antibody (Clone 9C10 (MFR-4-B)) (ABIN119958) specifically detects ITGA4 in FACS. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN119958
发货至: 中国
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Quick Overview for ITGA4 抗体 (FITC) (ABIN119958)

抗原

See all ITGA4 抗体
ITGA4 (Integrin alpha 4 (ITGA4))

适用

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人, 小鼠

宿主

  • 74
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大鼠

克隆类型

  • 119
  • 56
  • 2
单克隆

标记

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This ITGA4 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

9C10 (MFR-4-B)
  • 特异性

    This antibody recognises alpha 4 integrin (CD49d). Clone 9C10 (MFR4.B) is reported to significantly inhibit binding of CD49d to CD106 but only when used in combination with clone R1-2.

    纯化方法

    Affinity chromatography on Protein G

    免疫原

    Mouse LyD9 haematopoietic progenitor cells. Spleen cells from immunised Lewis rats were fused with cells of the mouse P3X63Ag8.653 myeloma cell line.

    亚型

    IgG2a
  • 应用备注

    Flow Cytometry: Neat - 1/2, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL, The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing. This antibody is photosensitive and should protected from light.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    ITGA4 (Integrin alpha 4 (ITGA4))

    别名

    CD49d / ITGA4

    背景

    CD49d is a 150kD glycoprotein that can associate with either beta 1 integrin (CD29) or beta 7 integrin to form heterodimers CD49d/CD29 (VLA-4) and alpha4/beta7 (LPAM-1) respectively. CD49d is expressed on most lymphocytes, granulocytes, monocytes and thymocytes. The primary ligands for CD49d are CD106 (VCAM-1), fibronectin and MAdCAM-1.Synonyms: CD49 antigen-like family member D, Integrin alpha-4, Integrin alpha-IV, VLA-4, VLA4

    基因ID

    16401

    NCBI登录号

    NP_034706

    UniProt

    Q00651

    途径

    Integrin Complex
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