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IL-10RA 抗体

IL10RA 适用: 小鼠 FACS, Func 宿主: 大鼠 Monoclonal 1B1-3a unconjugated
产品编号 ABIN119862
发货至: 中国
  • 抗原 See all IL-10RA (IL10RA) 抗体
    IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
    适用
    • 81
    • 39
    • 20
    • 6
    • 5
    • 2
    • 1
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    小鼠
    宿主
    • 73
    • 13
    • 10
    • 2
    大鼠
    克隆类型
    • 74
    • 22
    • 1
    单克隆
    标记
    • 50
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    • 1
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    This IL-10RA antibody is un-conjugated
    应用范围
    • 64
    • 30
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    • 14
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    • 7
    • 4
    • 3
    • 3
    • 2
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    • 1
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    Flow Cytometry (FACS), Functional Studies (Func)
    特异性
    This antibody recognises CDw210a, a cell surface glycoprotein of approximately 110KD, also known as Interleukin-10 receptor 1 (IL-10R1). The epitope recognised by this antibody has been localised to the ligand binding domain within the extracellular region of Mouse CDw210a. The specificity of this antibody has been confirmed by blocking with excess IL-10. This clone is reported to neutralize the effects of IL-10 (1). Does not react with Human.
    纯化方法
    Affinity Chromatography on Protein G
    免疫原
    Purified recombinant epitope tagged extracellular region of Mouse CDw210a (SMCD210-FLAG-His6). Spleen cells from immunised Fisher rats were fused with cells of the mouse SP2/0 myeloma cell line.
    克隆位点
    1B1-3a
    亚型
    IgG1
    Top Product
    Discover our top product IL10RA Primary Antibody
  • 应用备注
    Flow Cytometry: 1/10 - 1/100, Use 10 μL of the suggested working dilution to label 1x 10^6 cells in 100 μL, Due to low expression of CD210, sensitive staining techniques may be required. Functional Assays.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.4 without preservatives
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody at -20 °C. Ship at 2 - 8 °C.
  • 抗原
    IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
    别名
    CDw210a / IL10RA (IL10RA 产品)
    别名
    IL10R1 antibody, IL10RA antibody, CD210 antibody, CD210a antibody, CDW210A antibody, HIL-10R antibody, IL-10R1 antibody, IL10R antibody, AW553859 antibody, CDw210 antibody, CDw210a antibody, Il10r antibody, mIL-10R antibody, interleukin 10 receptor subunit alpha antibody, interleukin 10 receptor, alpha antibody, IL10RA antibody, Il10ra antibody
    背景
    Interleukin 10 binds specifically and with high affinity to cell-surface receptors. Interleukin 10 receptors are members of the class II subgroup of the cytokine receptor superfamily. The IL10 receptor complex contains two distinct type II cytokine receptor subunits, the ligand binding IL10RA and the IL10RB. The coexpression of both chains is essential for IL10 induced signal transduction. The beta chain serves as an accessory chain essential for the active IL10 receptor complex and necessary for the initiation of signal transdunction. Interleukin 10 receptors are expressed in all cell types that are known to respond to IL10. Mouse CDw210a is expressed by a range of cells including thymocytes, T cells, B cells and monocytes.Synonyms: IL-10R-A, IL10 Receptor alpha, Interleukin-10 receptor alpha chain
    基因ID
    16154
    NCBI登录号
    NP_032374
    UniProt
    Q61727
    途径
    Growth Factor Binding
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