Integrin Alpha2b 抗体 (PE)
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- 抗原 See all Integrin Alpha2b (CD41) 抗体
- Integrin Alpha2b (CD41)
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This Integrin Alpha2b antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 特异性
- This antibody recognises the integrin alpha IIb subunit CD41. Clone MWReg30 has been reported to inhibit PMA induced aggregation in vitro and to induce hypothermia in vivo. We recommend the use of SM2035A for use in functional studies.
- 交叉反应 (详细)
- Species reactivity (tested):Mouse.
- 纯化方法
- Affinity Chromatography on Protein G.
- 克隆位点
- MWReg30
- 亚型
- IgG1
- Top Product
- Discover our top product CD41 Primary Antibody
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- 应用备注
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Flow Cytometry: The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 溶解方式
- Restore with 1 mL distilled water
- 浓度
- 0.1 mg/mL
- 缓冲液
- PBS containing 0.09 % Sodium Azide as preservative, 5 % Sucrose and 1 % BSA as stabilizer.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
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- 抗原
- Integrin Alpha2b (CD41)
- 别名
- CD41 / ITGA2B (CD41 产品)
- 背景
- Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation. CD41 is expressed on platelets and megakaryocytes and forms a heterodimer with CD61. CD41/CD61 is important for platelet adhesion and aggregation.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb
- 基因ID
- 16399
- NCBI登录号
- NP_034705
- UniProt
- Q9QUM0
- 途径
- Integrin Complex
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