Integrin Alpha2b 抗体
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Quick Overview for Integrin Alpha2b 抗体 (ABIN119844)
抗原
See all Integrin Alpha2b (CD41) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognizes the integrin alpha IIb subunit CD41. Clone MWReg30 has been reported to inhibit PMA induced aggregation in vitro and to induce hypothermia in vivo (Nieswandt et al., 1999). SM2035A is recommended for use in functional studies.
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纯化方法
- Affinity Chromatography on Protein G.
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亚型
- IgG1
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anti-Integrin Alpha2b (CD41) (AA 45-149) antibody
CD41 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 2E10C9 unconjugated
anti-Integrin Alpha2b (CD41) (AA 45-149) antibodyCD41 适用: 人 FACS, WB, IHC, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-Integrin Alpha2b (CD41) (AA 351-450) antibodyCD41 适用: 人, 大鼠 FACS, WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 适用: 小鼠 FACS, ELISA, IP, IHC (fro), IHC (p), Func 宿主: 大鼠 Monoclonal MWReg30 unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 适用: 小鼠 FACS, ELISA, IP, IHC (fro), IHC (p) 宿主: 大鼠 Monoclonal MWReg30 unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 适用: 人, Non-Human Primate FACS, IHC (fro) 宿主: 小鼠 Monoclonal HIP2 unconjugated
anti-Integrin Alpha2b (CD41) antibody (Biotin)CD41 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-06 Biotin
anti-Integrin Alpha2b (CD41) antibody (FITC)CD41 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-06 FITC
anti-Integrin Alpha2b (CD41) (AA 677-711), (C-Term) antibodyCD41 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) (AA 639-887) antibodyCD41 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Flow Cytometry (1/50-1/100): Use 10 μL to label 10^6 cells in 100 μL. Immunohistology on Frozen Sections. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, containing 0.09 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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: "Intracerebral immune complex formation induces inflammation in the brain that depends on Fc receptor interaction." in: Acta neuropathologica, Vol. 124, Issue 4, pp. 479-90, (2012) (PubMed).
: "Protective and damaging effects of platelets in acute cholestatic liver injury revealed by depletion and inhibition strategies." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 115, Issue 1, pp. 286-94, (2010) (PubMed).
: "Regulation of proplatelet formation and platelet release by integrin alpha IIb beta3." in: Blood, Vol. 108, Issue 5, pp. 1509-14, (2006) (PubMed).
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: "Intracerebral immune complex formation induces inflammation in the brain that depends on Fc receptor interaction." in: Acta neuropathologica, Vol. 124, Issue 4, pp. 479-90, (2012) (PubMed).
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- Integrin Alpha2b (CD41)
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别名
- CD41 / ITGA2B
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背景
- CD41, a ~125 kDa single pass type 1 transmembrane glycoprotein, is expressed on platelets, megakaryocytes, mast cells and hematopoietic progenitors and forms a heterodimer with CD61. CD41/CD61 is important for platelet adhesion and aggregation.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb
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基因ID
- 16399
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NCBI登录号
- NP_034705
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UniProt
- Q9QUM0
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途径
- Integrin Complex
抗原
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