CD177 抗体
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北京 101111
Quick Overview for CD177 抗体 (ABIN119768)
抗原
See all CD177 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts with CD177 (Neutrophil specific antigen 1), a 60 kDa GPI-linked cell surface glycoprotein of uPAR family, expressed on granulocytes and in bone marrow early erythroblasts, megakaryocytes, promyelocytes and myelocytes.
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交叉反应 (详细)
- Species reactivity (tested):Human, Non-Human Primates.
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纯化方法
- Affinity Chromatography on Protein A
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免疫原
- Human Granulocytes
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亚型
- IgG1
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应用备注
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Flow cytometry. Immunoprecipitation. Western Blot under non-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH ~7.4, 15 mM Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated thawing and freezing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the original vial at 2-8 °C, stock solution or aliquots thereof at -20 °C.
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- CD177 (CD177 Molecule (CD177))
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别名
- CD177
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背景
- CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31(PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).Synonyms: HNA-2a, HNA2a, Human neutrophil alloantigen 2a, NB1, NB1 glycoprotein, PRV1, Polycythemia rubra vera protein 1
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基因ID
- 57126
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NCBI登录号
- NP_065139
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UniProt
- Q8N6Q3
抗原
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