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CD177 抗体

This anti-CD177 antibody is a 小鼠 单克隆 antibody detecting CD177 in WB, FACS 和 IP. Suitable for 人 和 灵长类.
产品编号 ABIN119768
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD177 抗体 (ABIN119768)

抗原

See all CD177 抗体
CD177 (CD177 Molecule (CD177))

适用

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人, 灵长类

宿主

  • 31
  • 22
小鼠

克隆类型

  • 33
  • 20
单克隆

标记

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This CD177 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

克隆位点

MEM-166
  • 特异性

    This antibody reacts with CD177 (Neutrophil specific antigen 1), a 60 kDa GPI-linked cell surface glycoprotein of uPAR family, expressed on granulocytes and in bone marrow early erythroblasts, megakaryocytes, promyelocytes and myelocytes.

    交叉反应 (详细)

    Species reactivity (tested):Human, Non-Human Primates.

    纯化方法

    Affinity Chromatography on Protein A

    免疫原

    Human Granulocytes

    亚型

    IgG1
  • 应用备注

    Flow cytometry. Immunoprecipitation. Western Blot under non-reducing conditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH ~7.4, 15 mM Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated thawing and freezing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the original vial at 2-8 °C, stock solution or aliquots thereof at -20 °C.
  • 抗原

    CD177 (CD177 Molecule (CD177))

    别名

    CD177

    背景

    CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31(PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).Synonyms: HNA-2a, HNA2a, Human neutrophil alloantigen 2a, NB1, NB1 glycoprotein, PRV1, Polycythemia rubra vera protein 1

    基因ID

    57126

    NCBI登录号

    NP_065139

    UniProt

    Q8N6Q3
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