CD177 抗体 (FITC)
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北京 101111
Quick Overview for CD177 抗体 (FITC) (ABIN119766)
抗原
See all CD177 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognises human CD177 (neutrophil glycoprotein NB1). The neutrophil NB1 antigen is expressed by 97 % of the caucasian population. Antibodies against NB1 can be involved in neonatal alloimmune neutropenia (NAN). Antibody reactivity and working conditions may vary between species.
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纯化方法
- Protein G affinity chromatography
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亚型
- IgG1
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应用备注
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Flow cytometry (use 10 μL of neat - 1/10 diluted antibody to label 10^6 cells in 100 μL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS with 0.09 % sodium azide as preservative and 1 % BSA as stabelizer
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2-8 °C for one month or (in small aliquots) at -20 °C for longer.
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- CD177 (CD177 Molecule (CD177))
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别名
- CD177
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背景
- Cd177 (NP1), a glycosyl phosphatidylinositol (GPI) linked N glycosylated cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia and analyses showed cell surface expression of a 60 kDa protein, 14 kDa greater than the predicted size, probably due to the presence of 3 potential N glycosylation sites. Immunohistochemistry demonstrated expression in bone marrow early erythroblasts, megakaryocytes, promyelocytes, and myelocytes. The neutrophil NB1 antigen (CD177) is expressed by 97 % of the caucasian population. Antibodies against NB1 can be involved in neonatal alloimmune neutropenia (NAN).Synonyms: HNA-2a, HNA2a, Human neutrophil alloantigen 2a, NB1, NB1 glycoprotein, PRV1, Polycythemia rubra vera protein 1
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基因ID
- 57126
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NCBI登录号
- NP_065139
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UniProt
- Q8N6Q3
抗原
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