MADCAM1 抗体
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北京 101111
Quick Overview for MADCAM1 抗体 (ABIN119567)
抗原
See all MADCAM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognises MAdCAM-1 (mucosal addressin cell adhesion molecule -1), a 40 kDa protein expressed by vascular endothelium. Clone CA102.2C1 has been reported to block the binding of human cells expressing alpha4 Beta7 to immobilized MAdCAM-1 in vitro.
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纯化方法
- Affinity chromatography on Protein A
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免疫原
- Bacterially expressed human MAdCAM-1.
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亚型
- IgG1
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应用备注
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ELISA. Western blotting. Functional assay.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS
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储存液
- Azide free
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody at -20 °C. Ship at 2 - 8 °C.
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- MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
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别名
- MAdCAM1
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背景
- MAdCAM1 is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM1 (alpha4 beta7), L selectin, and VLA4 (alpha4 beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full length nature of some variants has not been determined.Synonyms: MAdCAM-1, Mucosal addressin cell adhesion molecule 1, hMAdCAM-1
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基因ID
- 8174
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NCBI登录号
- NP_570116
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UniProt
- Q13477
抗原
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