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MADCAM1 抗体

MADCAM1 适用: 人 WB, EIA, Func 宿主: 小鼠 Monoclonal CA102-2C1 unconjugated
产品编号 ABIN119567
发货至: 中国
  • 抗原 See all MADCAM1 抗体
    MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
    适用
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    宿主
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    小鼠
    克隆类型
    • 47
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    单克隆
    标记
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    This MADCAM1 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)
    特异性
    This antibody recognises MAdCAM-1 (mucosal addressin cell adhesion molecule -1), a 40 kDa protein expressed by vascular endothelium. Clone CA102.2C1 has been reported to block the binding of human cells expressing alpha4 Beta7 to immobilized MAdCAM-1 in vitro.
    纯化方法
    Affinity chromatography on Protein A
    免疫原
    Bacterially expressed human MAdCAM-1.
    克隆位点
    CA102-2C1
    亚型
    IgG1
    Top Product
    Discover our top product MADCAM1 Primary Antibody
  • 应用备注
    ELISA. Western blotting. Functional assay.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS
    储存液
    Azide free
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody at -20 °C. Ship at 2 - 8 °C.
  • 抗原
    MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
    别名
    MAdCAM1 (MADCAM1 产品)
    别名
    MACAM1 antibody, AV211525 antibody, mucosal vascular addressin cell adhesion molecule 1 antibody, MADCAM1 antibody, Madcam1 antibody
    背景
    MAdCAM1 is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM1 (alpha4 beta7), L selectin, and VLA4 (alpha4 beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full length nature of some variants has not been determined.Synonyms: MAdCAM-1, Mucosal addressin cell adhesion molecule 1, hMAdCAM-1
    基因ID
    8174
    NCBI登录号
    NP_570116
    UniProt
    Q13477
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