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CD6 抗体

CD6 适用: 人 WB, FACS, IP, IHC (p) 宿主: 小鼠 Monoclonal MEM-98 unconjugated
产品编号 ABIN119554
发货至: 中国
  • 抗原 See all CD6 抗体
    CD6
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    宿主
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    小鼠
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    单克隆
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    This CD6 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    The antibody reacts with CD6, a 100-130 kDa single chain transmembrane glycoprotein expressed on T and B lymphocytes subsets, thymocytes, and acute lymphocytic leukemia cells.
    纯化方法
    Protein-A affinity chromatography
    纯度
    > 95 % pure (by SDS-PAGE)
    免疫原
    Human CD6 antigen purified by immunoaffinity chromatography from HBP-ALL cells followed by preparative SDS-PAGE of non-boiled non-reduced sample (excised piece of gel corresponding to the 100 kDa zone).
    克隆位点
    MEM-98
    亚型
    IgG1
    Top Product
    Discover our top product CD6 Primary Antibody
  • 应用备注
    Immunoprecipitation. Flow Cytometry. Western Blotting under non reducing conditions. Immunohistochemistry (paraffin sections): Recommended dilution: 10 m g/mL, Positive tissue: spleen.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing. Dilute only prior to immediate use
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody (undiluted) at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CD6
    别名
    CD6 (CD6 产品)
    别名
    TP120 antibody, OX52 antibody, CD6 antigen antibody, CD6 molecule antibody, Cd6 molecule antibody, Cd6 antibody, CD6 antibody
    背景
    CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.Synonyms: T-cell differentiation antigen CD6, T12, TP120
    基因ID
    923
    NCBI登录号
    NP_006716
    UniProt
    P30203
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