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CD43 抗体 (FITC)

SPN 适用: 人 FACS 宿主: 小鼠 Monoclonal DFT-1 FITC
产品编号 ABIN119529
发货至: 中国
  • 抗原 See all CD43 (SPN) 抗体
    CD43 (SPN) (Sialophorin (SPN))
    适用
    • 148
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    宿主
    • 96
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD43 antibody is conjugated to FITC
    应用范围
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    Flow Cytometry (FACS)
    特异性
    This antibody recognizes the CD43. Clone DFT-1 binds to both glycoforms of human CD43 (Kyoizumi et al. 2004).
    纯化方法
    Affinity Chromatography on Protein G.
    克隆位点
    DFT-1
    亚型
    IgG1
    Top Product
    Discover our top product SPN Primary Antibody
  • 应用备注
    Flow cytometry: use 10 μL of neat antibody to label 100 μL whole blood or 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.09 % Sodium Azide, 1 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CD43 (SPN) (Sialophorin (SPN))
    别名
    CD43 / Leukosialin (SPN 产品)
    别名
    CD43 antibody, GALGP antibody, GPL115 antibody, LSN antibody, A630014B01Rik antibody, Cd43 antibody, Galgp antibody, Ly-48 antibody, Ly48 antibody, Lsn antibody, Lsn1 antibody, gpL115 antibody, sialophorin antibody, SPN antibody, Spn antibody
    背景
    CD43 is one of the major glycoproteins of thymocytes and T lymphocytes, it plays a role in the physicochemical properties of the T cell surface and in lectin binding. CD43 presents carbohydrate ligands to selectins. It has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. The antigen is a counter receptor for SN/Siglec1. During T cell activation CD43 is actively removed from the T cell antigen presenting cell contact site suggesting a negative regulatory role in adaptive immune response. CD43 is expressed by the majority of leucocytes, with the exception of most B cells. However CD43 expression is seen in some cases of B cell lymphocytic lymphoma and centrocytic lymphoma.Synonyms: Galactoglycoprotein, Leukocyte sialoglycoprotein, SPN, Sialophorin
    基因ID
    6693
    NCBI登录号
    NP_001025459
    UniProt
    P16150
    途径
    Regulation of Leukocyte Mediated Immunity
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