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CD147 抗体

BSG 适用: 人 WB, FACS, IHC (p), IP 宿主: 小鼠 Monoclonal MEM-M6-1 unconjugated
产品编号 ABIN119255
发货至: 中国
  • 抗原 See all CD147 (BSG) 抗体
    CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD147 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
    特异性
    The antibody recognizes an epitope in the N-terminal Ig domain (D1) of CD147 (Neurothelin), a 50-60 kDa type I transmembrane glycoprotein primarily expressed on all leukocytes, red blood cells, platelets and endothelial cells, it is not expressed by resting lymphocytes. The antibody MEM-M6/1 is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography on Protein A
    免疫原
    Protein A-CR purified soluble recombinant form of CD147, CD147Rg, which consists of the cDNA coding for the hinge region, CH2-and CH3 domain of Human IgG1 (CD147Rg is secreted by transfectants as a dimer)
    克隆位点
    MEM-M6-1
    亚型
    IgG1
    Top Product
    Discover our top product BSG Primary Antibody
  • 应用备注
    Flow cytometry. Immunoprecipitation. Western blotting under non-reducing conditions (1 μg/mL). Immunohistochemistry (paraffin sections): Recommended dilution: 10 m g/mL Positive tissue: testis
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH ~7.4, 15 mM Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the original vial at 2-8 °C. Store stock solution or aliquots thereof at -20 °C.
  • 抗原
    CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
    别名
    CD147 (BSG 产品)
    别名
    EMMPRIN antibody, RPE7 antibody, 5F7 antibody, CD147 antibody, M6 antibody, OK antibody, TCSF antibody, AI115436 antibody, AI325119 antibody, HT-7 antibody, 5A11 antibody, CE9 antibody, HT7 antibody, Ox47R antibody, basignin antibody, wu:fb26a05 antibody, wu:fo98e12 antibody, bsg antibody, prso03 antibody, basigin (Ok blood group) antibody, basigin antibody, basigin (Ok blood group) S homeolog antibody, BSG antibody, Bsg antibody, bsg antibody, bsg.S antibody
    背景
    CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6) also known as EMMPRIN (extracellular matrix metalloproteinase inducer) or TCSF (tumour cell-derived collagenase-stimulatory factor) is an ubiquitously expressed cell surface protein with multiple glycosylated forms. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumour cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.Synonyms: 5F7, BSG, Basigin, Collagenase stimulatory factor, EMMPRIN, Extracellular matrix metalloproteinase inducer, Leukocyte activation antigen M6, OK blood group antigen, TCSF, Tumor cell-derived collagenase stimulatory factor
    基因ID
    682
    NCBI登录号
    NP_001719
    UniProt
    P35613
    途径
    S100 Proteins
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