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CD147 抗体

This anti-CD147 antibody is a 小鼠 单克隆 antibody detecting CD147 in WB, FACS, IP 和 IHC (p). Suitable for 人.
产品编号 ABIN119255
发货至: 中国

Quick Overview for CD147 抗体 (ABIN119255)

抗原

See all CD147 (BSG) 抗体
CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD147 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

MEM-M6-1
  • 特异性

    The antibody recognizes an epitope in the N-terminal Ig domain (D1) of CD147 (Neurothelin), a 50-60 kDa type I transmembrane glycoprotein primarily expressed on all leukocytes, red blood cells, platelets and endothelial cells, it is not expressed by resting lymphocytes. The antibody MEM-M6/1 is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography on Protein A

    免疫原

    Protein A-CR purified soluble recombinant form of CD147, CD147Rg, which consists of the cDNA coding for the hinge region, CH2-and CH3 domain of Human IgG1 (CD147Rg is secreted by transfectants as a dimer)

    亚型

    IgG1
  • 应用备注

    Flow cytometry. Immunoprecipitation. Western blotting under non-reducing conditions (1 μg/mL). Immunohistochemistry (paraffin sections): Recommended dilution: 10 m g/mL Positive tissue: testis
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH ~7.4, 15 mM Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the original vial at 2-8 °C. Store stock solution or aliquots thereof at -20 °C.
  • 抗原

    CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

    别名

    CD147

    背景

    CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6) also known as EMMPRIN (extracellular matrix metalloproteinase inducer) or TCSF (tumour cell-derived collagenase-stimulatory factor) is an ubiquitously expressed cell surface protein with multiple glycosylated forms. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumour cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.Synonyms: 5F7, BSG, Basigin, Collagenase stimulatory factor, EMMPRIN, Extracellular matrix metalloproteinase inducer, Leukocyte activation antigen M6, OK blood group antigen, TCSF, Tumor cell-derived collagenase stimulatory factor

    基因ID

    682

    NCBI登录号

    NP_001719

    UniProt

    P35613

    途径

    S100 Proteins
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