TSH receptor 抗体
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北京 101111
Quick Overview for TSH receptor 抗体 (ABIN119039)
抗原
See all TSH receptor (TSHR) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- 2C11 recognises both native and denatured TSH receptor (binding to an epitope at the carboxy terminus between amino acids 354 and 359). It does inhibit binding of TSH. No cross reactivity has been observed with related LH and FSH receptors. This antibody recognises the mutant TSH receptor known as I167N as well as the wild type molecule.
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纯化方法
- Affinity chromatography on Protein G
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免疫原
- Recombinant Human TSH receptor. Spleen cells from immunised BALB/c mice were fused with cells of the NS1/Ag4.1 mouse myeloma cell line.
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亚型
- IgG1
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应用备注
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Flow Cytometry. ELISA. Immunoprecipitation: 5-10 μg/mL. Western Blot: 5-10 μg/mL. Functional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
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别名
- Thyrotropin Receptor / TSHR
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背景
- The thyroid stimulating hormone (TSH) receptor (otherwise known as the thyrotropin receptor) is an important molecule in controlling the growth and function of the normal thyroid.Synonyms: LGR3, TSH-R, TSH-receptor, Thyroid-stimulating hormone receptor
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基因ID
- 7253
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NCBI登录号
- NP_000360
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UniProt
- P16473
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途径
- Thyroid Hormone Synthesis
抗原
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