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PLP1 抗体 (C-Term)

PLP1 适用: 人, Cow, 哺乳动物 WB, FACS, IF, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal plpc1 unconjugated
产品编号 ABIN119026
发货至: 中国
  • 抗原 See all PLP1 抗体
    PLP1 (Proteolipid Protein 1 (PLP1))
    抗原表位
    • 16
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 32
    • 25
    • 12
    • 9
    • 8
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    人, Cow, 哺乳动物
    宿主
    • 37
    • 10
    • 3
    小鼠
    克隆类型
    • 41
    • 9
    单克隆
    标记
    • 25
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PLP1 antibody is un-conjugated
    应用范围
    • 41
    • 19
    • 16
    • 13
    • 13
    • 12
    • 8
    • 6
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody recognizes Myelin Proteolipid protein (PLP) in many Mammalian species. This antibody also recognizes DM20.
    交叉反应 (详细)
    Species reactivity (tested):Bovine.
    纯化方法
    Affinity Chromatography on Protein A from Tissue Culture Supernatant
    免疫原
    Synthetic peptide CGRGTKF corresponding to C-terminal region of Myelin Proteolipid Protein. Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
    克隆位点
    Plpc1
    亚型
    IgG2a
    Top Product
    Discover our top product PLP1 Primary Antibody
  • 应用备注
    Western blot. Immunohistochemistry on Frozen Sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    PLP1 (Proteolipid Protein 1 (PLP1))
    别名
    PLP1 (PLP1 产品)
    别名
    GPM6C antibody, HLD1 antibody, MMPL antibody, PLP antibody, PLP/DM20 antibody, PMD antibody, SPG2 antibody, Plp antibody, PLP1 antibody, plp1 antibody, DKFZp459O081 antibody, DKFZp459O113 antibody, DM20 antibody, jimpy antibody, jp antibody, msd antibody, rsh antibody, plp antibody, hld1 antibody, mmpl antibody, plp1a antibody, pmd antibody, spg2 antibody, DMalpha2c antibody, wu:fc27f01 antibody, wu:fj36d03 antibody, wu:fj42d08 antibody, zgc:110499 antibody, PLP-B antibody, plp1-a antibody, plp1-b antibody, plp1b antibody, proteolipid protein 1 antibody, proteolipid protein (myelin) 1 antibody, myelin proteolipid protein antibody, proteolipid protein 1 L homeolog antibody, proteolipid protein 1a antibody, proteolipid protein 1 S homeolog antibody, PLP1 antibody, Plp1 antibody, plp1 antibody, Tsp_11640 antibody, plp antibody, plp1.L antibody, plp1a antibody, plp1.S antibody
    背景
    Myelin proteins are associated with the central nervous system (CNS) and play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. The proteolipid protein (PLP) and its splice variant DM20 are the predominant myelin proteins in the CNS. PLP is also one of the most extensively studied myelin proteins because of the prevelance of PLP mutations amongst humans and animals. Such mutations can lead to abnormal myelin formation resulting in conditions such as X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. PLP encodes the major protein components of compact CNS myelin and mutations in the PLP gene can lead to severe dysmyelinating disease.Synonyms: Lipophilin, Myelin proteolipid protein, PLP
    基因ID
    281410
    NCBI登录号
    NP_776574
    UniProt
    P04116
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