alpha Defensin 1 抗体
Quick Overview for alpha Defensin 1 抗体 (ABIN118975)
抗原
See all alpha Defensin 1 (DEFA1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Several Defensins are recognized. This antibody recognises a family of Cyclic Peptides in Neutrophils. Human: Defensin 1-3 (HNP-1 to HNP-3) in Human Neutrophils. Synthetic Defensin-1 and -2 (Bachem, Bubendorf CH) stain also positively. Not tested with Defensin-4. A side reaction to elastin has been observed in humans. Other: not tested. Defensins have been described in rabbits (NP-1 to NP-5, NP3a = Corticostatin), and in mice (cryptodin).
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纯化方法
- Affinity chromatography
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免疫原
- Native defensins. The epitope has not been further characterized.
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亚型
- IgG1
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anti-Defensin, alpha 1 (DEFA1) (AA 1-94) antibody
DEFA1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Defensin, alpha 1 (DEFA1) (AA 20-94) antibodyDEFA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Defensin, alpha 1 (DEFA1) (AA 20-93) antibodyDEFA1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Defensin, alpha 1 (DEFA1) (AA 1-94) antibodyDEFA1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Defensin, alpha 1 (DEFA1) antibodyDEFA1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Defensin, alpha 1 (DEFA1) antibodyDEFA1 适用: 人 WB, IHC, ELISA, Neut, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-Defensin, alpha 1 (DEFA1) antibodyDEFA1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Defensin, alpha 1 (DEFA1) (AA 28-62) antibodyDEFA1 适用: 人 WB 宿主: 兔 Polyclonal RB57879 unconjugated
anti-Defensin, alpha 1 (DEFA1) (Internal Region) antibodyVerified DEFA1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Immunohistochemistry on Frozen Sections: 0.2 μg/mL (1/1000). Immunohistochemistry on Paraffin Sections: 0.5 μg/mL (1/400), Proteinase K pretreatmentfor antigen retrieval is recommended. Positive Control: Human tonsil. Has been discribed to work in FACS with permeabilized cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with 0.5 mL distilled water.
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浓度
- 0.2 mg/mL
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缓冲液
- PBS, pH 7.2, containing 5 mg/mL BSA and 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the lyophilised antibody at 2-8 °C and after reconstitution at -20 °C.
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- alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))
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别名
- Defensin alpha 1
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背景
- Defensins are a family of cyclic peptides containing 29-35 amino acids (MW < 3500) which tend to form aggregates. Four of these peptides are described in humans (HNP-1 to 4), six in rabbits (NP-1 to 5). Synonyms are MCP-1 for NP-1, MCP-2 for NP-2 and corticostatin for NP-3. Biological Functions: Various functions have been described for defensins. They are antibacterial, antifungal, chemotactic for monocytes, inhibitory for ACTH-induced corticosteroid synthesis and cytotoxic for cells. Defensins are inhibited by glucosaminoglycans (self protection for cells) and high concentrations of Ca2+ ions.Synonyms: DEF-1, DEF-3, DEF-A1, DEF-A2, DEF-A3, DEF1, DEF3, DEFA-1, DEFA-2, DEFA-3, DEFA1, DEFA2, DEFA3, Defensin alpha 1, Defensin alpha 3, HNP-1, HNP-3, HNP1, HNP3, HP-1, HP-3, HP1, HP3, MRS, Neutrophil defensin 1, Neutrophil defensin 3
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基因ID
- 1667
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NCBI登录号
- NP_001035965
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UniProt
- P59665
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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