TCR alpha/beta 抗体 (Chain alpha)
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北京 101111
Quick Overview for TCR alpha/beta 抗体 (Chain alpha) (ABIN118909)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Chain alpha
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity Chromatography on Protein A
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亚型
- IgG2a
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anti-T Cell Receptor alpha/beta (TCR alpha/beta) antibody (FITC)
TCR alpha/beta 适用: 人 FACS 宿主: 小鼠 Monoclonal IP26 FITC
anti-T Cell Receptor alpha/beta (TCR alpha/beta) antibody (PE)TCR alpha/beta 适用: 大鼠, Non-Human Primate FACS 宿主: 小鼠 Monoclonal R73 PE
anti-T Cell Receptor alpha/beta (TCR alpha/beta) antibodyTCR alpha/beta 适用: 大鼠, Non-Human Primate FACS, IP, IHC (fro), WB, IHC (p), ICC 宿主: 小鼠 Monoclonal R73 unconjugated
anti-T Cell Receptor alpha/beta (TCR alpha/beta) antibodyTCR alpha/beta 适用: 人 FACS 宿主: 小鼠 Monoclonal IP26 unconjugated
anti-T Cell Receptor alpha/beta (TCR alpha/beta) antibody (FITC)TCR alpha/beta 适用: 大鼠, Non-Human Primate FACS 宿主: 小鼠 Monoclonal R73 FITC
anti-T Cell Receptor alpha/beta (TCR alpha/beta) antibody (PerCP)TCR alpha/beta 适用: 人 FACS 宿主: 小鼠 Monoclonal IP26 PerCP
anti-T Cell Receptor alpha/beta (TCR alpha/beta) antibody (APC)TCR alpha/beta 适用: 人 FACS 宿主: 小鼠 Monoclonal IP26 APC
anti-T Cell Receptor alpha/beta (TCR alpha/beta) antibody (PE)TCR alpha/beta 适用: 人 FACS 宿主: 小鼠 Monoclonal IP26 PE
anti-T Cell Receptor alpha/beta (TCR alpha/beta) antibody (Biotin)TCR alpha/beta 适用: 人 FACS 宿主: 小鼠 Monoclonal IP26 Biotin
anti-T Cell Receptor alpha/beta (TCR alpha/beta) antibodyTCR alpha/beta 适用: 大鼠, Non-Human Primate FACS, IP, IHC (fro), WB, IHC (p), Func, ICC 宿主: 小鼠 Monoclonal R73 unconjugated
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应用备注
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Immunohistochemistry on frozen sections. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.09 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
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- TCR alpha/beta (T Cell Receptor alpha/beta (TCR alpha/beta))
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别名
- T Cell Receptor (TCR) alpha/beta
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背景
- T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor beta locus. The beta locus includes V (variable), J (joining), diversity (D), and C (constant) segments. During T cell development, the beta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment, a V segment is then joined to the D-J gene. The C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Several V segments and one J segment of the beta locus are known to be incapable of encoding a protein and are considered pseudogenes. The beta locus also includes eight trypsinogen genes, three of which encode functional proteins and five of which are pseudogenes. Chromosomal abnormalities involving the T-cell receptor beta locus have been associated with T-cell lymphomas.Synonyms: T-Cell Receptor alpha, T-Cell Receptor alpha beta, T-Cell Receptor beta, TCRA, TCRB
抗原
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