FCAR 抗体
Quick Overview for FCAR 抗体 (ABIN118855)
抗原
See all FCAR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognises the CD89 cell surface antigen. Clone MIP8a blocks binding of IgA to the Fc alpha R, and also inhibits neutrophil phagocytosis of IgA complexes. The preservative free format of this antibody (product code SM1198A) is recommended for functional studies.
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Purified
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免疫原
- Recombinant soluble Human Fc alpha R
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亚型
- IgG1
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anti-Fc Fragment of IgA, Receptor For (FCAR) (AA 22-227) antibody
FCAR 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2F9D8 unconjugated
anti-Fc Fragment of IgA, Receptor For (FCAR) (AA 51-280) antibodyFCAR 适用: 大鼠 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgA, Receptor For (FCAR) antibodyFCAR 适用: 人 WB, FACS, ELISA, IP 宿主: 小鼠 Monoclonal MIP8a unconjugated
anti-Fc Fragment of IgA, Receptor For (FCAR) antibodyFCAR 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgA, Receptor For (FCAR) antibodyFCAR 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal A59 unconjugated
anti-Fc Fragment of IgA, Receptor For (FCAR) antibody (APC)FCAR 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal A59 APC
anti-Fc Fragment of IgA, Receptor For (FCAR) (AA 131-230) antibodyFCAR 适用: 人, 大鼠 ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgA, Receptor For (FCAR) (AA 58-84) antibodyFCAR 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgA, Receptor For (FCAR) (AA 1-287) antibodyFCAR 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Fc Fragment of IgA, Receptor For (FCAR) antibody (FITC)FCAR 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal A59 FITC
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应用备注
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Flow Cytometry: Use 10 μL of 1/50-1/100 diluted antibody to label 10^6 cells or 100 μL whole blood. ELISA. Immunoprecipitation. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.09 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FCAR (Fc Fragment of IgA, Receptor For (FCAR))
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别名
- CD89 / FCAR
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背景
- CD89 cell surface antigen is a 50-70kD glycoprotein that is also known as the IgA receptor. CD89 is expressed by peripheral blood neutrophils and monocytes. Human CD89 is present on a number of cell types, including neutrophils, monocytes, macrophages, and eosinophils. FCAR interacts with aggregated IgAs, such as IgA coated on the surface of an invading microorganism, and mediates several immunologic defense processes such as phagocytosis, antibody dependent cell mediated cytotoxicity, and stimulation of the release of inflammatory mediators. FCAR is a glycoprotein of 50 to 100 kD, with diversity on different cell types.Synonyms: IgA Fc receptor, Immunoglobulin alpha Fc receptor
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基因ID
- 2204
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NCBI登录号
- NP_001991
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UniProt
- P24071
抗原
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