CD57 recognizes a (Mr 100-110 kDa) oligosaccharide antigenic determinant on myeloid cells and on a variety of polypeptides, lipids and chondroitan sulfate proteoglycans. This surface antigen is associated with myelin-associated glycoprotein (MAG). The CD57 antigen is present on 15-20 % of normal peripheral blood mononuclear cells. It is expressed on a subset of natural killer cells (60 %) and on a subset of T-lymphocytes. This carbohydrate is also present on N-CAM in the nervous system.Synonyms: HNK-1, LEU7, NK-1, NK-Cell marker, NK1