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ITGA2 抗体 (PE)

ITGA2 适用: 人, 猴 FACS 宿主: 小鼠 Monoclonal AK7 PE
产品编号 ABIN118701
发货至: 中国
  • 抗原 See all ITGA2 抗体
    ITGA2 (Integrin alpha 2 (ITGA2))
    适用
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    人, 猴
    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This ITGA2 antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS)
    特异性
    Recognizes the Integrin alpha 2 subunit (CD49b), which is a 160 kDa glycoprotein that non-covalently associates with the 130 kDa integrin beta1 subunit to form the VLA-2 complex.
    纯化方法
    Affinity Chromatography on Protein G
    克隆位点
    AK7
    亚型
    IgG1
    Top Product
    Discover our top product ITGA2 Primary Antibody
  • 应用备注
    Flow Cytometry: Use 10 μL of neat antibody to label 10^6 cells or 100 μL human whole blood.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore with 1.0 mL distilled water.
    缓冲液
    PBS, pH 7.2 with 0.09 % Sodium Azide as preservative, 1 % BSA and 5 % Sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
  • 抗原
    ITGA2 (Integrin alpha 2 (ITGA2))
    别名
    CD49b / ITGA2 (ITGA2 产品)
    别名
    BR antibody, CD49B antibody, GPIa antibody, HPA-5 antibody, VLA-2 antibody, VLAA2 antibody, DX5 antibody, integrin subunit alpha 2 antibody, integrin alpha 2 antibody, ITGA2 antibody, Itga2 antibody
    背景
    Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. They are responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. CD49b is a 160kD glycoprotein that non-covalently associates with the 130kD integrin beta 1 subunit to form the VLA-2 complex. CD49b is expressed by platelets, long term cultivated T cells, approximately 50 % of monocytes and most adherent cell lines.Synonyms: CD49 antigen-like family member B, Collagen Receptor, GPIa, ITGA-2, Integrin alpha-2, Platelet membrane glycoprotein Ia, VLA-2 alpha, VLA2
    基因ID
    3673
    NCBI登录号
    NP_002194
    UniProt
    P17301
    途径
    CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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