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IL-2 抗体 (FITC)

This anti-IL-2 antibody is a 大鼠 单克隆 antibody detecting IL-2 in FACS. Suitable for 小鼠.
产品编号 ABIN118386
发货至: 中国

Quick Overview for IL-2 抗体 (FITC) (ABIN118386)

抗原

See all IL-2 (IL2) 抗体
IL-2 (IL2) (Interleukin 2 (IL2))

适用

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小鼠

宿主

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大鼠

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单克隆

标记

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This IL-2 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

JES6-5H4
  • 特异性

    This antibody recognises natural and recombinant IL-2. This antibody may be used to detect intracellular IL-2 in flow cytometric applications.

    纯化方法

    Affinity chromatography on Protein G

    免疫原

    Recombinant Mouse IL-2. Spleen cells from immunised BALB/c mice were fused with cells of the mouse P3.X63 Ag8.653 myeloma cell line.

    亚型

    IgG2b
  • 应用备注

    Flow Cytometry: neat - 1/10, use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL, Membrane permeabilisation is required for this application. in 100 μL
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    IL-2 (IL2) (Interleukin 2 (IL2))

    别名

    Interleukin-2 / IL2

    背景

    Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.Synonyms: IL-2, T-cell growth factor, TCGF

    基因ID

    16183

    NCBI登录号

    NP_032392

    UniProt

    P04351

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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