ITGA6 抗体
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- 抗原 See all ITGA6 抗体
- ITGA6 (Integrin, alpha 6 (ITGA6))
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适用
- 人, 小鼠, 犬, Pig, 猴
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This ITGA6 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
- 特异性
- The monoclonal antibody is directed against the CDw49f-antigen. This monoclonal NKI-GoH3 antibody reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukaemia cells (alpha-6 beta-1). In immunohistology the monoclonal antibody reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytiotrophoblasts. Platelet VLA-6 functions as a laminin receptor and platelet adhesion to laminin is inhibited by GoH3. Studies suggest that Clone NKI-GoH3 specifically blocks the binding of cells to the E8 fragment of laminin (See Sonnenberg, A. et al. for details).
- 纯化方法
- Affinity Chromatography on Protein G
- 免疫原
- BALB/c mouse mammary tumour cells. Spleen cells from immunised Sprague-Dawley rats were fused with cells of the SP2/0 mouse myeloma cell line.
- 克隆位点
- NKI-GoH3
- 亚型
- IgG2a
- Top Product
- Discover our top product ITGA6 Primary Antibody
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anti-Integrin, alpha 6 (ITGA6) (Internal Region) antibody
ITGA6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 6 (ITGA6) antibodyITGA6 适用: 人 FACS, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 129CT49-6-5 unconjugated
anti-Integrin, alpha 6 (ITGA6) (Ser1064) antibodyITGA6 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 6 (ITGA6) (AA 1082-1110), (C-Term) antibodyITGA6 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18006 unconjugated
anti-Integrin, alpha 6 (ITGA6) (AA 1043-1072), (Isoform 2) antibodyITGA6 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB15309 unconjugated
anti-Integrin, alpha 6 (ITGA6) (AA 625-866) antibodyITGA6 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 6 (ITGA6) antibodyITGA6 适用: 人, 小鼠, 犬, Pig, 绵羊, Cynomolgus FACS, IHC (fro), IP 宿主: 大鼠 Monoclonal NKI-GoH3 unconjugated
anti-Integrin, alpha 6 (ITGA6) (Internal Region) antibodyITGA6 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 6 (ITGA6) (AA 24-133) antibodyITGA6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C1 unconjugated
anti-Integrin, alpha 6 (ITGA6) (AA 1-1073) antibodyITGA6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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Flow cytometry. Immunohistochemistry on frozen sections. Recommended positive control: Human Tonsil. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS, pH 7.4, 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- ITGA6 (Integrin, alpha 6 (ITGA6))
- 别名
- CD49f / ITGA6 (ITGA6 产品)
- 背景
- CDw49f-antigen is a 120kD, (GP Ic or VLA-6 alpha-chain), which can form distinct complexes with either the CD29-antigen (GP 11a or VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells.Synonyms: CD49 antigen-like family member F, Integrin alpha-6, VLA-6, VLA6
- 基因ID
- 3655
- NCBI登录号
- NP_000201
- UniProt
- P23229
- 途径
- CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
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