ITGA6 抗体 (FITC)
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- 抗原 See all ITGA6 抗体
- ITGA6 (Integrin, alpha 6 (ITGA6))
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适用
- 人, 小鼠, 犬, Pig, 猴, 绵羊
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This ITGA6 antibody is conjugated to FITC
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应用范围
- Flow Cytometry (FACS)
- 特异性
- This antibody recognises CD49F (VLA-6 alpha chain). Clone NKI-GoH3 reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukaemia cells (alpha-6 beta-1). In immunohistology the monoclonal antibody reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytotrophoblasts. VLA-6 is an important mediator of cell binding to laminin. Studies suggest that clone GoH3 specifically blocks the binding of cells to the E8 fragment of laminin.
- 纯化方法
- Affinity chromatography on Protein G
- 免疫原
- BALB/c mouse mammary tumour cells. Spleen cells from immunised Sprague-Dawley rats were fused with cells of the SP2/0 mouse myeloma cell line.
- 克隆位点
- NKI-GoH3
- 亚型
- IgG2a
- Top Product
- Discover our top product ITGA6 Primary Antibody
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- 应用备注
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Flow cytometry: Use 10 μL of neat antibody to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.1 mg/mL
- 缓冲液
- PBS containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- ITGA6 (Integrin, alpha 6 (ITGA6))
- 别名
- CD49f / ITGA6 (ITGA6 产品)
- 背景
- CD49f is a 120kD cell surface glycoprotein that can form distinct complexes with CD29 (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells.Synonyms: CD49 antigen-like family member F, Integrin alpha-6, VLA-6, VLA6
- 基因ID
- 3655
- NCBI登录号
- NP_000201
- UniProt
- P23229
- 途径
- CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
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