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CD38 抗体

This anti-CD38 antibody is a 大鼠 单克隆 antibody detecting CD38 in FACS, IP 和 IHC (fro). Suitable for 小鼠.
产品编号 ABIN118188
发货至: 中国

Quick Overview for CD38 抗体 (ABIN118188)

抗原

See all CD38 抗体
CD38

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD38 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

9E1
  • 特异性

    This antibody recognises the CD38 cell surface antigen.

    纯化方法

    Purified

    免疫原

    Mouse pre-B cells derived from IL-7 dependent bone marrow cultures

    亚型

    IgG2a
  • 应用备注

    Flow cytometry: 1/2- 1/20, use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunoprecipitation. Immunohistochemistry on frozen sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    PBS containing 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C
  • 抗原

    CD38

    背景

    CD38 (T10) is a single chain 42 to 46 kDa type II integral transmembrane glycoprotein with a short N terminal cytoplasmic tail. CD38 is highly expressed on thymocytes. It is also expressed by early cells of B and T lineages, NK cells, plasma cells, monocytes and macrophages and may be detected on cells from multiple myeloma, ALL (B and T) and some AML. It is expressed by murine, but not human, hematopoietic progenitors. In normal lymph nodes and tonsils the antigen is detected mainly on B cells in germinal centers and in plasma cells. The extracellular domain of the molecule shares a high homology sequence with Aplysia ADP ribosyl cyclase. CD38 functions as a multicatalytic ectoenzyme serving as ADP ribosyl cyclase, ADPR hydrolase and possibly NAD+ glycohydrolase, or as a surface receptor.Synonyms: ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, T10, cADPr hydrolase 1

    基因ID

    12494

    NCBI登录号

    NP_031672

    UniProt

    P56528
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