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ING5 抗体 (AA 127-140)

ING5 适用: 人, 猴 WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN118053
发货至: 中国
  • 抗原 See all ING5 抗体
    ING5 (Inhibitor of Growth Family, Member 5 (ING5))
    抗原表位
    • 7
    • 7
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 127-140
    适用
    • 40
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 猴
    宿主
    • 36
    • 3
    • 1
    山羊
    克隆类型
    • 40
    多克隆
    标记
    • 20
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ING5 antibody is un-conjugated
    应用范围
    • 28
    • 21
    • 6
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    序列
    Protein Sequence: Human p28 ING5 isoform 1, 240 aa, predicted MW 27.8 kDa: 1 matamylehy ldsienlpce lqrnfqlmre ldqrtedkka eidilaaeyi stvktlspdq 61 rverlqkiqn ayskckeysd dkvqlamqty emvdkhirrl dadlarfead lkdkmegsdf 121 essggrglkk grgqkekrgs rgrgrrtsee dtpkkkkhkg gseftdtils vhpsdvldmp 181 vdpneptycl chqvsygemi gcdnpdcpie wfhfacvdlt kpkgkwfcp rcvqekrkkk Protein Sequence: Human p28 ING5 isoform 2, 226 aa, predicted MW 25.9 kDa 1 matamylehy ldsienlpce lqrnfqlmre ldqrtedkka eidilaaeyi stvktlspdq 61 verlqkiqn ayskckeysd dkvqlamqty emvdkhirrl dadlarfead lkdkmegsdf 121 essggrglkk grgqkekrgs rgrgrrtsee dtpkkkkhkg gseftdtils vhpsdvldmp 181 vdpneptycl chqvsygemi gcdnpdcpie wfhfacvdlt tkpkgk
    特异性
    This is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase. Reactivity occurs against human p28 ING5 protein. The sequence is present in both isoforms 1 and 2 (see below). However, 100 % homology is on record for this protein from human and chimpanzee. Cross reactivity with p28 ING5 protein from frog, mouse, rat and chicken may not occur as sequence homology varies by one or more amino acids residues in this sequence as indicated by BLAST analysis. Reactivity with p28 ING5 proteins from other sources is not known.
    纯化方法
    Immunoaffinity chromatography.
    免疫原
    This affinity purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 127-140 of Human p28 ING5protein (Inhibitor of growth family, member 5). This sequence shows homology to isoforms 1 and 2 for ING5.
    Top Product
    Discover our top product ING5 Primary Antibody
  • 应用备注
    This affinity purified antibody has been tested for use in ELISA (1: 4,000 - 1: 16,000) and byWestern blot (1: 500-1: 1,000, Expect a band approximately 28 kDa or 26 kDa in sizecorresponding to variants of ING5 in the appropriate cell lysate or extract). Also suitable for Immunofluorescence microscopy.
    限制
    仅限研究用
  • 浓度
    1.2 mg/mL (UVabs. 280 nm)
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % sodium azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Dilute only prior to immediate use. Avoid cycles of freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store vial at -20 °C or below prior to opening. Aliquot contents and freeze at -20 °C or below.
  • 抗原
    ING5 (Inhibitor of Growth Family, Member 5 (ING5))
    别名
    ING5 (ING5 产品)
    别名
    p28ING5 antibody, 1700001C14Rik antibody, 1700027H23Rik antibody, 1810018M11Rik antibody, AI225768 antibody, p28ing5 antibody, MGC76007 antibody, ING5 antibody, MGC133862 antibody, ING1 antibody, p33 antibody, si:busm1-40g1.1 antibody, si:dz40g1.1 antibody, wu:fc94a02 antibody, zgc:100910 antibody, ing5 antibody, inhibitor of growth family member 5 antibody, inhibitor of growth family, member 5 antibody, inhibitor of growth family member 5 L homeolog antibody, inhibitor of growth family, member 5b antibody, inhibitor of growth family, member 5a antibody, ING5 antibody, Ing5 antibody, ing5 antibody, ing5.L antibody, ing5b antibody, ing5a antibody
    背景
    ING5 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. ING5 is a component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. ING5 acts as a tumor suppressor and is a potent growth regulator in normal and in established cells. ING5 may have involvement in chromatin remodeling.Synonyms: Inhibitor of growth protein 5, p28ING5
    基因ID
    84289
    NCBI登录号
    NP_115705
    UniProt
    Q8WYH8
    途径
    Chromatin Binding
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