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Cullin 3 抗体 (N-Term)

Name: Cullin 3 抗体 (N-Term)
SKU: ABIN117949
Availability: OutOfStock

This anti-Cullin 3 antibody is a 兔多克隆 antibody detecting Cullin 3 in WB, IHC (p), IP 和 EIA. Suitable for 人和小鼠. This Primary Antibody has been cited in 1 publication.

Conjugation pathways for ubiquitin and ubiquitin-like modifiers (UBLs). (Cullin 3 抗体 (N-Term))

1 image

(1 reference)

产品编号 ABIN117949

发货至: 中国

Datasheet as PDF

Quick Overview for Cullin 3 抗体 (N-Term) (ABIN117949)

抗原

See all Cullin 3 (CUL3) 抗体

Cullin 3 (CUL3)

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This Cullin 3 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Discover our top product CUL3 Primary Antibody

抗原表位
15

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2

1

1

1

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1

1

1

1

1
AA 1-12, N-Term

序列

Human Cullin 3 (768 aa 88.9 kDa): 1 msnlskgtgs rkdtkmrira fpmtmdekyv nsiwdllkna iqeiqrknns glsfeelyrn 61 aytmvlhkhg eklytglrev vtehlinkvr edvlnslnnn flqtlnqawn dhqtamvmir 121 dilmymdrvy vqqnnvenvy nlgliifrdq vvrygcirdh lrqtlldmia rerkgevvdr 181 gairnacqml milglegrsv yeedfeapfl emsaeffqme sqkflaensa svyikkvear 241 ineeiervmh cldksteepi vkvverelis khmktiveme nsglvhmlkn gktedlgcmy 301 klfsrvpngl ktmcecmssy lreqgkalvs eegegknpvd yiqglldlks rfdrfllesf 361 nndrlfkqti agdfeyflnl nsrspeylsl fiddklkkgv kglteqevet ildkamvlfr 421 fmqekdvfer yykqhlarrl ltnksvsdds eknmisklkt ecgcqftskl egmfrdmsis 481 nttmdefrqh lqatgvslgg vdltvrvltt gywptqsatp kcnippaprh afeifrrfyl 541 akhsgrqltl qhhmgsadln atfygpvkke dgsevgvgga qvtgsntrkh ilqvstfqmt 601 ilmlfnnrek ytfeeiqqet diperelvra lqslacgkpt qrvltkepks keienghift 661 vndqftsklh rvkiqtvaak qgesdperke trqkvdddrk heieaaivri mksrkkmqhn 721 vlvaevtqql karflpspvv ikkrieglie reylartped rkvytyva

特异性

This product is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. This product reacts with human Cullin 3. Cross reactivity is expected against mouse Cul3 based on sequence homology. Cross reactivity with other human cullins is unlikely based on sequence homology.

纯化方法

Delipidation and defibrination.

免疫原

Synthetic peptide corresponding to amino acids 1-12 of Human Cul3 (N-terminus) coupled to KLH.
anti-Cullin 3 (CUL3) antibody
CUL3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

anti-Cullin 3 (CUL3) (AA 411-510) antibody
CUL3 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Cullin 3 (CUL3) antibody
CUL3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Cullin 3 (CUL3) antibody
CUL3 适用: 人 IHC, ELISA 宿主: 兔 Monoclonal 7B6 unconjugated Recombinant Antibody

anti-Cullin 3 (CUL3) (AA 618-667) antibody
CUL3 适用: 人, 斑马鱼, Cow, 小鸡, 犬, 豚鼠, 马, 兔, 猴, Bat, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Cullin 3 (CUL3) (AA 301-400) antibody
CUL3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A3 unconjugated

anti-Cullin 3 (CUL3) (N-Term) antibody
CUL3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Cullin 3 (CUL3) antibody
CUL3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Cullin 3 (CUL3) (Internal Region) antibody
Verified CUL3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Cullin 3 (CUL3) (N-Term) antibody
CUL3 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot: This antibody reacts with human Cul3 (1/500-1/1,000, An 88.9 kDa bandcorresponding to human Cul3 is detected, Most cell lines expressing Cul3 can be used as apositive control).

限制

仅限研究用
状态

Liquid

浓度

85.0 mg/mL (by Refractometry)

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store undiluted at 2-8 °C for up to one month or at -20 °C for longer.
Chuang, Huang, Hsieh, Jung, Ye, Du, Lu, Cho, Hsiao, Hsu, Lin: "Sporadic paediatric and adult Burkitt lymphomas share similar phenotypic and genotypic features." in: Histopathology, Vol. 52, Issue 4, pp. 427-35, (2008) (PubMed).
抗原

Cullin 3 (CUL3)

别名

Cullin-3

背景

Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse polyubiquitination, as well as binding to various specificity factors to recruit substrates. Cullin 3 is an essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, cul3 serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. Cul3 may also contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Unlike Cul1 and Cul2, Cul3 seems not to be a part of the SCF complex consisting of CUL1, RBX1, SKP1 and SKP2. Cul3 also interacts with RNF7 and is part of a complex with TIP120A/CAND1, Cyclin E and RBX1.Synonyms: CUL-3, CUL3, KIAA0617

基因ID

8452

NCBI登录号

NP_003581

UniProt

Q13618

途径

M Phase