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ZNF148 抗体

ZNF148 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN117932
发货至: 中国
  • 抗原 See all ZNF148 抗体
    ZNF148 (Zinc Finger Protein 148 (ZNF148))
    适用
    • 43
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    宿主
    • 43
    • 1
    克隆类型
    • 44
    多克隆
    标记
    • 27
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    This ZNF148 antibody is un-conjugated
    应用范围
    • 36
    • 19
    • 12
    • 9
    • 4
    • 4
    • 2
    • 1
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    Western Blotting (WB), Enzyme Immunoassay (EIA)
    序列
    1 mniddklegl flkcggidem qssrtmvvmg gvsgqstvsg elqdsvlqdr smphqeilaa 61 devlqesemr qqdmishdel mvheetvknd eeqmetherl pqglqyalnv pisvkqeitf 121 tdvseqlmrd kkqirepvdl qkkkkrkqrs pakiltined gslglktpks hvcehcnaaf 181 rtnyhlqrhv fihtgekpfq csqcdmrfiq kyllqrheki htgekpfrcd ecgmrfiqky 241 hmerhkrths gekpyqceyc lqyfsrtdrv lkhkrmchen hdkklntcai kgglltseed 301 sgfstspkdn slpkkkrqkt ekkssgmdke saldksdlkk dkndylpvys sstkvkdeym 361 vaeyavemph ssvggshled asgeihppkl vlkkinskrs lkqpleqnqt isplstyees 421 kvskyafelv dkqalldseg nadidqvdnl qegpskpvhs stnyddamqf lkkkrylqaa 481 snnsreyaln vgtirsqpsv tqaavasvid esttasiles qalnveiksn hdknvipdev 541 lqtlldhysh kangqheisf svadtevtss isinssevpe vtpsenvgss sqasssdkan 601 mlqeyskflq qaldrtsqnd aylnspslnf vtdnqtlpnq pafssidkqv yatmpinsfr 661 sgmnsplrtt pdkshfgliv gdsqhsfpfs gdetnhasat stqdfldqvt sqkkaeaqpv 721 hqayqmssfe qpfrapyhgs ragiatqfst angqvnlrgp gtsaefsefp lvnvndnrag 781 mtsspdattg qtfg
    特异性
    This polyclonal antibody is specific for ZBP-89.
    纯化方法
    Delipidation and defibrination
    免疫原
    Purified full length ZBP-89 recombinant protein expressed in E.coli
    Top Product
    Discover our top product ZNF148 Primary Antibody
  • 应用备注
    This polyclonal antibody reacts human ZBP-89 in a variety of immunological assaysincluding western blot and ELISA. This antibody is likely functional inimmunohistochemistry and immunoprecipitation. Recommended dilutionsImmunoblotting: 1: 5,000. A band at approximately 89 kDa corresponding to human ZBP-89is detected. Human monocytes or macrophages or nuclear extracts from PMA treated U937cells can be used as a positive control. ELISA: 1: 10,000 - 1: 30,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    90 mg/mL (by Refractometry)
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • 抗原
    ZNF148 (Zinc Finger Protein 148 (ZNF148))
    别名
    ZNF148 (ZNF148 产品)
    别名
    BERF-1 antibody, BFCOL1 antibody, HT-BETA antibody, ZBP-89 antibody, ZFP148 antibody, pHZ-52 antibody, 2210405J08Rik antibody, AI480666 antibody, AW045217 antibody, Znf148 antibody, Zbp-89 antibody, fb06h05 antibody, wu:fb06h05 antibody, zfp149 antibody, zgc:165342 antibody, SLC12A8 antibody, zinc finger protein 148 antibody, ZNF148 antibody, Zfp148 antibody, znf148 antibody
    背景
    The GI tract abundantly expresses growth factors many of which bind and activate the EGF receptor present on mucosal cells. One such factor is the zinc finger protein (ZBP-89) that binds to a GC-rich DNA element in the gastrin promoter and confers EGF responsiveness. The fulllength protein functions as a repressor of growth factor signals regulating the gastrin promoter. Several other growth related promoters are also regulated by ZBP-89. ZBP-89 is one of a family of related transcriptional regulators. It has been reported in recent studies that ZBP-89 regulates growth in part by stimulating the cyclin-dependent kinase inhibitor, p21waf1, in a butyrate-dependent manner through recruitment of the histone acetyl transferase p300. Moreover, ZBP-89 triggers growth arrest in a p53-dependent manner by preventing nuclear export of p53. ZBP-89 also induces apoptosis, but this process occurs independent of p53.Synonyms: Transcription factor ZBP-89, ZBP89, Zinc finger DNA-binding protein 89, Zinc finger protein 148
    基因ID
    7707
    NCBI登录号
    NP_068799
    UniProt
    Q9UQR1
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