ZNF148 抗体
Quick Overview for ZNF148 抗体 (ABIN117932)
抗原
See all ZNF148 抗体适用
宿主
克隆类型
标记
应用范围
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序列
- 1 mniddklegl flkcggidem qssrtmvvmg gvsgqstvsg elqdsvlqdr smphqeilaa 61 devlqesemr qqdmishdel mvheetvknd eeqmetherl pqglqyalnv pisvkqeitf 121 tdvseqlmrd kkqirepvdl qkkkkrkqrs pakiltined gslglktpks hvcehcnaaf 181 rtnyhlqrhv fihtgekpfq csqcdmrfiq kyllqrheki htgekpfrcd ecgmrfiqky 241 hmerhkrths gekpyqceyc lqyfsrtdrv lkhkrmchen hdkklntcai kgglltseed 301 sgfstspkdn slpkkkrqkt ekkssgmdke saldksdlkk dkndylpvys sstkvkdeym 361 vaeyavemph ssvggshled asgeihppkl vlkkinskrs lkqpleqnqt isplstyees 421 kvskyafelv dkqalldseg nadidqvdnl qegpskpvhs stnyddamqf lkkkrylqaa 481 snnsreyaln vgtirsqpsv tqaavasvid esttasiles qalnveiksn hdknvipdev 541 lqtlldhysh kangqheisf svadtevtss isinssevpe vtpsenvgss sqasssdkan 601 mlqeyskflq qaldrtsqnd aylnspslnf vtdnqtlpnq pafssidkqv yatmpinsfr 661 sgmnsplrtt pdkshfgliv gdsqhsfpfs gdetnhasat stqdfldqvt sqkkaeaqpv 721 hqayqmssfe qpfrapyhgs ragiatqfst angqvnlrgp gtsaefsefp lvnvndnrag 781 mtsspdattg qtfg
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特异性
- This polyclonal antibody is specific for ZBP-89.
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纯化方法
- Delipidation and defibrination
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免疫原
- Purified full length ZBP-89 recombinant protein expressed in E.coli
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anti-Zinc Finger Protein 148 (ZNF148) antibody
ZNF148 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 148 (ZNF148) (AA 690-794) antibodyZNF148 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 148 (ZNF148) (N-Term) antibodyZNF148 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 148 (ZNF148) (N-Term) antibodyZNF148 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 148 (ZNF148) antibodyZNF148 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 148 (ZNF148) (AA 690-794) antibodyZNF148 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 148 (ZNF148) (AA 106-135), (N-Term) antibodyZNF148 适用: 人 WB 宿主: 兔 Polyclonal RB40518 unconjugated
anti-Zinc Finger Protein 148 (ZNF148) (N-Term) antibodyZNF148 适用: 人, Cow WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 148 (ZNF148) (N-Term) antibodyZNF148 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 148 (ZNF148) (AA 695-794) antibodyZNF148 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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This polyclonal antibody reacts human ZBP-89 in a variety of immunological assaysincluding western blot and ELISA. This antibody is likely functional inimmunohistochemistry and immunoprecipitation. Recommended dilutionsImmunoblotting: 1: 5,000. A band at approximately 89 kDa corresponding to human ZBP-89is detected. Human monocytes or macrophages or nuclear extracts from PMA treated U937cells can be used as a positive control. ELISA: 1: 10,000 - 1: 30,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 90 mg/mL (by Refractometry)
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
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- ZNF148 (Zinc Finger Protein 148 (ZNF148))
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别名
- ZNF148
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背景
- The GI tract abundantly expresses growth factors many of which bind and activate the EGF receptor present on mucosal cells. One such factor is the zinc finger protein (ZBP-89) that binds to a GC-rich DNA element in the gastrin promoter and confers EGF responsiveness. The fulllength protein functions as a repressor of growth factor signals regulating the gastrin promoter. Several other growth related promoters are also regulated by ZBP-89. ZBP-89 is one of a family of related transcriptional regulators. It has been reported in recent studies that ZBP-89 regulates growth in part by stimulating the cyclin-dependent kinase inhibitor, p21waf1, in a butyrate-dependent manner through recruitment of the histone acetyl transferase p300. Moreover, ZBP-89 triggers growth arrest in a p53-dependent manner by preventing nuclear export of p53. ZBP-89 also induces apoptosis, but this process occurs independent of p53.Synonyms: Transcription factor ZBP-89, ZBP89, Zinc finger DNA-binding protein 89, Zinc finger protein 148
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基因ID
- 7707
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NCBI登录号
- NP_068799
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UniProt
- Q9UQR1
抗原
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